Protein Alignment Cyp6a22 and Cyp6t1

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_608457.1
• Gene: Cyp6t1 / 33127
• FlyBaseID: FBgn0031182
• Length: 529
• Species: Drosophila melanogaster
• Alignment Length: 549
• Identity: 172/549 - (31%)
• Similarity: 254/549 - (46%)
• Gaps: 85/549 - (15%)

  Fly     1 MLDVVALLLIALAVG---------------------------FWFVRTRYSYWTRRGIGSEPARF 38
            |:.|.:|:..|||||                           ||       :|.|.|:...||..
  Fly     1 MIAVFSLIAAALAVGSLVLLPVVLRGGCLLVVTIVWLWQILHFW-------HWRRLGVPFVPAAP 58

  Fly    39 PVGNMEGFRKNK-HFIDIVTPIYEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFED 102
            .|||:....:.. .|.|....:||..:..|..|.|..::....:|:.|..|.|:|:::|||.|..
  Fly    59 FVGNVWNLLRGACCFGDQFRELYESKEAAGRAFVGIDVLHNHALLLRDPALIKRIMVEDFAQFSS 123

  Fly   103 RGMYHNERDDPL-----TGHLFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGE 162
            |    .|..||.     :.:||......||...:..:|.|.:.|::.|:..:..:|::|.:...:
  Fly   124 R----FETTDPTCDTMGSQNLFFSKYETWRETHKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQ 184

  Fly   163 LADNAMCGILEIGDLMARYTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIE 227
            .........||:..|.|.:|:|:|...|||:|.:.|:||||||          ||.|..|:.
  Fly   185 KLSGRDSMELEVKQLCALFTTDIIASLAFGIEAHSLQNPEAEF----------RRMCIEVND--- 236

  Fly   228 SFPEVARFLRM-------RQIHQDIT----DFYVGIVRET----VKQREEQGIVRSDFMNLLIEM 277
              |...|.|.:       |..|:..|    :.|...:|::    :.||.|.|..|.|.:::.:::
  Fly   237 --PRPKRLLHLFTMFFFPRLSHRVGTHLYSEEYERFMRKSMDYVLSQRAESGENRHDLIDIFLQL 299

  Fly   278 K--QRGELTIEE---MAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALR-LHN 336
            |  :..|..|..   .||||.....||||||:||:.||||||||...:|.:||.|:..||: ..:
  Fly   300 KRTEPAESIIHRPDFFAAQAAFLLLAGFDTSSSTITFALYELAKNTTIQDRLRTELRAALQSSQD 364

  Fly   337 GEFTYDSMQELRYMELVIAETLRKYPILPQLTRI--SRHLYAA---KGDRHFYIEPGQMLLIPVY 396
            .:.:.|::..|.|:..|:.|.||.||....|.|.  ||..|..   .|...|.:..|..:.|.|.
  Fly   365 RQLSCDTVTGLVYLRQVVDEVLRLYPPTAFLDRCCNSRTGYDLSPWNGGSPFKLRAGTPVYISVL 429

  Fly   397 GIHHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFH 461
            |||.|...:|.|..|.||||.|:|..|.....:||||.|||.|||...|:::..:||:.:|.:|.
  Fly   430 GIHRDAQYWPNPEVFDPERFSAEQRQQHHPMTYLPFGAGPRGCIGTLLGQLEIKVGLLHILNHFR 494

  Fly   462 FSVCPRTDPKIEFLKSNILLCPANGIYLK 490
            ..||.||.|::.|.....:|...||.||:
  Fly   495 VEVCERTLPEMRFDPKAFVLTAHNGTYLR 523

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	159/488 (33%)
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	144/442 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461071
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900