Protein Alignment Cyp6a22 and Cyp6v1

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001285499.1
• Gene: Cyp6v1 / 33056
• FlyBaseID: FBgn0031126
• Length: 520
• Species: Drosophila melanogaster
• Alignment Length: 532
• Identity: 167/532 - (31%)
• Similarity: 274/532 - (51%)
• Gaps: 60/532 - (11%)

  Fly     4 VVALLLIALAVGFWFVRTRYSYWTRRGIGSEPARFPVGNM-------EGF--RKNKHFIDIVTPI 59
            ::|::.|...|..|..|| |.||.||.:........:||:       |.|  :..:.:.|
  Fly     8 LLAIVTILTGVFIWSRRT-YVYWQRRRVKFVQPTHLLGNLSRVLRLEESFALQLRRFYFD----- 66

  Fly    60 YEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTG-HLFRIDG 123
             |:|:..  |..|.::..:|.:|:.||:|.:.:|::||.:|.:|....:.|.|.:.. .||....
  Fly    67 -ERFRNE--PVVGIYLFHQPALLIRDLQLVRTVLVEDFVSFSNRFAKCDGRSDKMGALSLFLAKQ 128

  Fly   124 PKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCG------ILEIGDLMARYT 182
            |:||.:|.:::|.|..||:|.||..:.|:|.:|......|..:...|      |:.|.|:...|.
  Fly   129 PEWREIRTRLAPAFAGAKLKQMFSLMEEIGCDLEWYLKRLTRDLRRGDAERGAIVSIKDVCDLYN 193

  Fly   183 SDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHC---------KLVDGFIESF-PEVARFLR 237
            :|:|...|||:....|||.::|..          .||         :::|.|:..: |::...||
  Fly   194 TDMIASIAFGLRSYSLRNTQSEIG----------SHCQDLFRPNVRRIIDLFVIFYLPKLVPLLR 248

  Fly   238 MRQIHQDITDFYVGIVRETVKQREEQGIVRSDFMNLLIEMKQRGELTIEE---------MAAQAF 293
            .:...:...:|...:::..:::||..|.:|:|.:.:|:.:|:..:|..::         :||||.
  Fly   249 PKLFTEPHAEFLRRVIQLVIEERERGGDLRNDLIEMLLTLKKEADLQQDKSHFTHHRDFLAAQAA 313

  Fly   294 IFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLH-NGEFTYDSMQELRYMELVIAET 357
            .|..||.:|.::::.||||||||||.:|::||.||.:|...: ||..||:::..:.::::|:.||
  Fly   314 SFEVAGIETCSASMSFALYELAKQPLMQSRLRREIREAFASNPNGRLTYEAVARMEFLDMVVEET 378

  Fly   358 LRKYPILPQLTR-----ISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFL 417
            ||||||:|.|.|     ..:..|:.:.....|...|..:.|....|||||..:|:|.:|.||||.
  Fly   379 LRKYPIVPLLERECTPINKKRFYSLRPHAECYTRRGMPVFISNLAIHHDPKYWPDPDRFDPERFS 443

  Fly   418 ADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLC 482
            |...|.:...:::|||.||||||||:.|.:|..:|||..|......:|.||..:|:|.....||.
  Fly   444 AANKALQAPMSYMPFGAGPRNCIGMQIGLLQIKLGLVYFLHQHRVEICDRTVERIQFDAKFALLA 508

  Fly   483 PANGIYLKVQQL 494
            ....|||||..|
  Fly   509 SEQRIYLKVDCL 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	153/496 (31%)
Cyp6v1	NP_001285499.1	p450	59..517	CDD:299894	149/475 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461119
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8426
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900