Protein Alignment Cyp6a22 and LOC3291548

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_551896.3
• Gene: LOC3291548 / 3291548
• VectorBaseID: AGAMI1_006144
• Length: 545
• Species: Anopheles gambiae
• Alignment Length: 558
• Identity: 170/558 - (30%)
• Similarity: 264/558 - (47%)
• Gaps: 73/558 - (13%)

  Fly     2 LDVVALLLIALAVGFWFVRTRYSYWTR----------RGIGSEPARFPVGNMEGFRKNKHFIDIV 56
            :::..::|:.|.....|:   |.|.|:          ..:.:||.......:  ..|...|.|.|
Mosquito     1 MEISLMVLVPLVAILGFI---YHYITKGNKYFHDKPIPSLAAEPLFGSTRRL--MMKQTSFHDFV 60

  Fly    57 TPIYEKFKGNGAPFAGFFMM---LRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHL 118
            ..||.|:     |....|.|   :.|:.:|.|.||.|:|.::||..|.:........|||....|
Mosquito    61 ISIYNKY-----PLVKVFGMIDTMLPMFVVRDPELLKRIAVKDFEYFMNHRPVFGNNDDPHNEAL 120

  Fly   119 F-----RIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGIL--EIGD 176
            |     .|...|||.:|..:||.||.:||:.||..:.|....:.|...|...:...|..  |:.|
Mosquito   121 FGKTLIAITDQKWRDMRATLSPAFTGSKMRQMFELIVECSSNMAQHYKEQIRSNGAGSREHEMKD 185

  Fly   177 LMARYTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVD--GFIESFPEVARFLRMR 239
            :..||.:|||..||||::.:.|::.|.:|.:.|::..:..|...::.  || ...|::..|..:.
Mosquito   186 VFTRYANDVIATCAFGIKVDSLKHAENDFFVNGKKMMAFNRPIVMLRMMGF-RLLPKLMNFFNLD 249

  Fly   240 QIHQDITDFYVGIVRETVKQREEQGIVRSDFMNLLIEMKQ---------------RGELTIE--- 286
            ...::...|:..|:::||:.|:..||||.|.::||::.::               :|..|:|
Mosquito   250 LFDREQRVFFTEIIKDTVRTRDANGIVRPDMVHLLMQARKGALKHQRDTEEREEVKGFATVEESE 314

  Fly   287 ---------------EMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEI---DQALR 333
                           ||.||..|||.|||||.::.|.|..|||.....:|.||.|||   |:|
Mosquito   315 VGQTQASKGMQMTELEMIAQCLIFFLAGFDTVSTCLTFLAYELTVNRDVQDKLYEEILQTDKA-- 377

  Fly   334 LHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRIS-RHLYAAKGDR-HFYIEPGQMLLIPVY 396
            |..|..|||::|.::||::|::|.||.:...|...|:. |......||| .|.|:.|.::.||:.
Mosquito   378 LSGGPLTYDAVQGMQYMDMVVSEGLRMWAPAPATDRLCVRDYVVDDGDRLKFTIDKGTVVFIPIA 442

  Fly   397 GIHHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFH 461
            |:||||..||.|.||.||||..:...:.....:||||.|||||||.||..|:....:..:||.|.
Mosquito   443 GLHHDPQYYPNPSKFDPERFSVENRDKINPNTYLPFGIGPRNCIGSRFALMEVKAIIYYMLREFS 507

  Fly   462 FSVCPRTDPKIEFLKSNILLCPANGIYLKVQQLSQMSS 499
            |...|.|...:...|....:....|::::.:...|.::
Mosquito   508 FERTPNTQVPLRLAKGFAGMRSEKGVFVEFRPRKQAAN 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	154/471 (33%)
LOC3291548	XP_551896.3	CYP6-like	71..534	CDD:410679	153/465 (33%)