Protein Alignment Cyp6a22 and Cyp4d1

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_476907.2
• Gene: Cyp4d1 / 31188
• FlyBaseID: FBgn0005670
• Length: 512
• Species: Drosophila melanogaster
• Alignment Length: 563
• Identity: 137/563 - (24%)
• Similarity: 223/563 - (39%)
• Gaps: 127/563 - (22%)

  Fly     2 LDVVALLLIALAVGFWFVRTRY-------SYWTRRGIGSEPARFPVGNMEGFRKNKHFI-----D 54
            |.:.|:|..||.||......::       ||     :...|....||:      ..|||     :
  Fly     3 LVIGAILASALFVGLLLYHLKFKRLIDLISY-----MPGPPVLPLVGH------GHHFIGKPPHE 56

  Fly    55 IVTPIYEKFKGNGAPFAGFFMMLRPVVLV-----TDLELAKQILIQDFANFEDRGMYHNERDDPL 114
            :|..|:| |....:......:.|.|.:.|     .|:|:....|     .|.|:...:...:..|
  Fly    57 MVKKIFE-FMETYSKDQVLKVWLGPELNVLMGNPKDVEVVLGTL-----RFNDKAGEYKALEPWL 115

  Fly   115 TGHLFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDL-M 178
            ...|....|.||...|:.::|.| ..|:...|..|.|.|..      :|..|.....|:.||. .
  Fly   116 KEGLLVSRGRKWHKRRKIITPAF-HFKILDQFVEVFEKGSR------DLLRNMEQDRLKHGDSGF 173

  Fly   179 ARY------TSDVIGRCAFGVECNGLRNPEAEFA--------IMGRRAF---------------- 213
            :.|      |.|.|...|.||..|...|.::|:.        ::.:|.|
  Fly   174 SLYDWINLCTMDTICETAMGVSINAQSNADSEYVQAVKTISMVLHKRMFNILYRFDLTYMLTPLA 238

  Fly   214 -SERRHCKLVDGFIESF-----PEVARFLRMRQIHQDITDFYVGIVRETVKQREEQGIVRSDFMN 272
             :|::...::..|.|..     .|:.|....::...|..|  ||..|:..            |::
  Fly   239 RAEKKALNVLHQFTEKIIVQRREELIREGSSQESSNDDAD--VGAKRKMA------------FLD 289

  Fly   273 LL----IEMKQRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALR 333
            :|    ::.:....|.|.| ....|:|  .|.||::|.|.|..|.:|..|..|.|..|||...
  Fly   290 ILLQSTVDERPLSNLDIRE-EVDTFMF--EGHDTTSSALMFFFYNIATHPEAQKKCFEEIRSV-- 349

  Fly   334 LHNGEFT---YDSMQELRYMELVIAETLRKYPILPQLTR-------ISRHLYAAKGDRHFYIEPG 388
            :.|.:.|   |:.:.:|.|::|.:.||||.||.:|.|.|       |:..|          |..|
  Fly   350 VGNDKSTPVSYELLNQLHYVDLCVKETLRMYPSVPLLGRKVLEDCEINGKL----------IPAG 404

  Fly   389 QML-LIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTA-AWLPFGDGPRNCIGMRFGKMQTTI 451
            ..: :.|:| :.....|:.||:.|.||||.....|::... |::||..|||||||.:|..::...
  Fly   405 TNIGISPLY-LGRREELFSEPNIFKPERFDVVTTAEKLNPYAYIPFSAGPRNCIGQKFAMLEIKA 468

  Fly   452 GLVSLLRNFHFS-VCPRTDPKIEFLKSNILLCPANGIYLKVQQ 493
            .:.::||::... |...::|.:  |.:.::|.....:..||::
  Fly   469 IVANVLRHYEVDFVGDSSEPPV--LIAELILRTKEPLMFKVRE 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	116/480 (24%)
Cyp4d1	NP_476907.2	CYP4	73..504	CDD:410721	116/474 (24%)