Protein Alignment Cyp6a22 and erg5

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_593788.2
• Gene: erg5 / 2542469
• PomBaseID: SPAC19A8.04
• Length: 543
• Species: Schizosaccharomyces pombe
• Alignment Length: 544
• Identity: 117/544 - (21%)
• Similarity: 218/544 - (40%)
• Gaps: 122/544 - (22%)

  Fly     5 VALLLIALAVGFWFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPIYEKF--KGNG 67
            :...|:|:.:.:    .:.||..::|....| ||.:..|..      |:|.:.|.:||:  |...
pombe    31 ICFALLAVCIAY----DQISYQMQKGHIPGP-RFKIPFMGS------FLDSMKPTFEKYNAKWQT 84

  Fly    68 APFAGFFMMLRPVVLVTDLELAKQIL-----IQDFANFEDRG---MYHNERDDPLTGHLFRIDGP 124
            .|.:...:..:.||:.::.:||::||     :|...  .|.|   :.|       |..:| :||.
pombe    85 GPLSCVSVFHKFVVIASERDLARKILNSPSYVQPCV--VDAGKKILKH-------TNWVF-LDGR 139

  Fly   125 KWRPLRQKMSPTFTSAKM------------KYMFPTVCEVGEELTQVCGELAD-------NAMCG 170
            .....|:.::..||:..:            ||....:....::..|......|       ...||
pombe   140 DHIEYRKGLNGLFTTRALASYLPAQEAVYNKYFKEFLAHSKDDYAQYMIPFRDINVATSCRTFCG 204

  Fly   171 ILEIGDLMARYTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARF 235
            .. |.|...::.:|...:....:|                               :.:||.|..|
pombe   205 YY-ISDDAIKHIADEYWKITAAME-------------------------------LVNFPIVLPF 237

  Fly   236 LRM---RQIHQDITDFYVGIVRETVKQRE---EQGIVRSDFMNLLIEMK------QRG------- 281
            .::   .|..:.:..:::....|:.|..|   ....:..::::.:||.:      :.|
pombe   238 TKVWYGIQSRKVVMRYFMKAAAESRKNMEAGNAPACMMEEWIHEMIETRKYKSENKEGAEKPSVL 302

  Fly   282 --ELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGE----FT 340
              |.:.||::.....|..|..|.::|.:.:....||..|.:..|:|||   .||:..|:    .:
pombe   303 IREFSDEEISLTFLSFLFASQDATSSAMTWLFQLLADHPDVLQKVREE---QLRIRKGDIDVPLS 364

  Fly   341 YDSMQELRYMELVIAETLR-KYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIP-VYGIHHDPA 403
            .|.|:::.|...|:.|.|| :.|:|....|:.: .:....|   |..|...::|| :||..||..
pombe   365 LDLMEKMTYTRAVVKECLRLRPPVLMVPYRVKK-AFPITPD---YTVPKDAMVIPTLYGALHDSK 425

  Fly   404 LYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRF--GKMQTTIGLVSLLRNFHFSVCP 466
            :||||..|.|:|:..:.||::....|:.||:||..|:|.|:  ..:...||..|::.::.....|
pombe   426 VYPEPETFNPDRWAPNGLAEQSPKNWMVFGNGPHVCLGQRYAVNHLIACIGKASIMLDWKHKRTP 490

  Fly   467 RTDPKIEFLKSNILLCPANGIYLK 490
            .:|.::.|..:    .|.:..|||
pombe   491 DSDTQMIFATT----FPQDMCYLK 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	99/477 (21%)
erg5	NP_593788.2	CYP61_CYP710	85..507	CDD:410703	99/474 (21%)