Protein Alignment Cyp6a22 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_036819.1
• Gene: Tbxas1 / 24886
• RGDID: 3826
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 540
• Identity: 153/540 - (28%)
• Similarity: 259/540 - (47%)
• Gaps: 80/540 - (14%)

  Fly     5 VALLLIALAVGFWFVRTRYSYWTRRGI-GSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKGNGA 68
            |.|.::.||:..|:..:.:|...:.|| ..||:.| |||:..||:.  |.:....:.|::    .
  Rat    18 VTLSVVLLALLKWYSTSAFSRLRKLGIRHPEPSPF-VGNLMFFRQG--FWESHLELRERY----G 75

  Fly    69 PFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRIDGPKWRPLRQKM 133
            |..|:::..|..::::|.::.|::|:::|:||.:| |........:...:..:...:|..:|..:
  Rat    76 PLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNR-MASGLEPKLIADSVLMLRDRRWEEVRGAL 139

  Fly   134 SPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCG-ILEIGDLMARYTSDVIGRCAFGVECNG 197
            ...|:..|:..|.|.:.:..|.|   ...|..:|..| ..:|......:|::|:...|||:|.|.
  Rat   140 MSAFSPEKLNEMTPLISQACELL---LSHLKHSAASGDAFDIQRCYCCFTTNVVASVAFGIEVNS 201

  Fly   198 LRNPEAEFAIMGRRAFSERRHCKLVDGF---------IESFPEV----ARFLRMRQIHQDITDFY 249
            ...||..|.          :||:.|..|         |.|||.:    ||.|..:. ..::..|:
  Rat   202 QDAPEDPFV----------QHCQRVFAFSTPRPLLALILSFPSIMVPLARILPNKN-RDELNGFF 255

  Fly   250 VGIVRETVKQREEQGIV--RSDFMNLLIEMKQ----------------------RGE-------- 282
            ..::|..:..|::|...  |.||:.::::.::                      .|:
  Rat   256 NTLIRNVIALRDKQTAEERRGDFLQMVLDAQRSMSSVGVEAFDMVTEALSSAECMGDPPQRCHPT 320

  Fly   283 -----LTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYD 342
                 ||::|:|.|||:|..||.:.:.:||.|..|.||..|..|.:|.:|:|..:..|... .|.
  Rat   321 STAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERLLKEVDLFMEKHPAP-EYC 384

  Fly   343 SMQE-LRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYP 406
            ::|| |.|:::|:|||||.||...:.||.:.......|.   :|..|.:|.|.|..:||||..:|
  Rat   385 NLQEGLPYLDMVVAETLRMYPPAFRFTREAAQDCEVLGQ---HIPAGSVLEIAVGALHHDPEHWP 446

  Fly   407 EPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPK 471
            .|..|.||||.|:...|:....:||||.|||:|:|:|.|.:...:.|:.:|..|.|..||.|...
  Rat   447 NPETFDPERFTAEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFEACPETQVP 511

  Fly   472 IEFLKSNILLCPANGIYLKV 491
            :: |:|...|||.||:|:|:
  Rat   512 LQ-LESKSALCPKNGVYVKI 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	133/473 (28%)
Tbxas1	NP_036819.1	cytochrome_P450	74..527	CDD:477761	133/476 (28%)