Protein Alignment Cyp6a22 and cyp-13A1

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001369869.1
• Gene: cyp-13A1 / 188361
• WormBaseID: WBGene00011677
• Length: 519
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 142/540 - (26%)
• Similarity: 240/540 - (44%)
• Gaps: 119/540 - (22%)

  Fly     6 ALLLIALAVGFWFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKGNGAPF 70
            |:.:...:...|    ::::|.|||:.. |..||                |..::.....|..||
 Worm    11 AIFVAVFSYYIW----QWTFWRRRGVVG-PMGFP----------------VLGVFLNSLDNNFPF 54

  Fly    71 A--------------GFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTG----- 116
            .              ||.......::::|.||..::.:..:.||      :..:.:|:.|
 Worm    55 PLQCREWTKKFGKIYGFTEGTLKTLVISDPELVHEVFVTQYDNF------YGRKRNPIQGDSEKE 113

  Fly   117 ---HLFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQ-VCGELADNAMCGILEIGDL 177
               :||...|.:|:.||...||||:::.::.::.||.:...||.: :..:.|......:|:   .
 Worm   114 KRTNLFAAQGFRWKRLRAISSPTFSNSSLRKLYQTVEDSALELLRHIEKQSAGGKQIDMLK---F 175

  Fly   178 MARYTSDVIGRCAFG-VECNGLRNP---------EAEFAIMGRRAFSERRHCKLVDGFIESF-PE 231
            ...:|.|||||.|.| .:....:||         :..||    :.|       |:.|...:| .|
 Worm   176 YQEFTLDVIGRIAMGQTDSQMFKNPIMPIVSKLFQGNFA----KLF-------LIGGIFPTFLVE 229

  Fly   232 VARFLRMRQI----HQDITDFYVGIVRETVKQREE---QGI---VRSDFMNLLIEMKQR-----G 281
            :.|.:.::.:    .:.|.:..:..:...:|||||   .||   ..:||::|.::.|..     |
 Worm   230 IIRQILLKNLKVGSFRKINEITLDAIHNRIKQREEDQKNGIEIGEPADFIDLFLDAKAEDVEHFG 294

  Fly   282 E---------------LTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQA 331
            |               ||.||:..|..:|..|||||:|.:|.:|.|.||..|.:|.||:||:::
 Worm   295 ENNGDFSKSTTYTNRQLTTEEIVGQCTVFLIAGFDTTALSLSYATYLLATHPEIQKKLQEEVNR- 358

  Fly   332 LRLHNGEFTYDSMQELRYMELVIAETLRKYPI--LPQLTRISRHLYAAKGDRHFYIEPGQMLLIP 394
             ...|.|.|.|.:.:|:|||.|..|.||.||:  .....|..|:....    :..:|.|.|:.:.
 Worm   359 -ECPNPEVTIDQLSKLKYMECVFKEALRLYPLGAFANSRRCMRNTKLG----NMKVEVGTMIQVD 418

  Fly   395 VYGIHHDPALY-PEPHKFIPERFL---ADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVS 455
            .:.:|.||.:: .:...|.|||:.   :||:.|:  :.::|||.|||.|||||...|:..|.||.
 Worm   419 TWTLHTDPNIWGDDAEDFKPERWQTPNSDQIYQK--SGYIPFGLGPRQCIGMRLAYMEEKILLVH 481

  Fly   456 LLRNFHFSVCPRTDPKIEFL 475
            :||.|.|....:|:..::.:
 Worm   482 ILRKFTFETGAKTEIPLKLI 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	132/480 (28%)
cyp-13A1	NP_001369869.1	CYP3A-like	64..510	CDD:410678	129/466 (28%)