Protein Alignment Cyp6a22 and cyp-13A3

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_496110.1
• Gene: cyp-13A3 / 188359
• WormBaseID: WBGene00011675
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 547
• Identity: 146/547 - (26%)
• Similarity: 238/547 - (43%)
• Gaps: 98/547 - (17%)

  Fly     7 LLLIALAVG-FWFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPI--YEK------ 62
            |:.|||.:| |.:....:|:|.|:|| ..|...|            |..|:...  |||
 Worm     6 LIAIALFIGVFTYYLWIWSFWMRKGI-KGPRGLP------------FFGIINAFQSYEKPWILRL 57

  Fly    63 --FKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTG--------H 117
              :.....|..||...:...::|:|.|...::.::.|.||..|      :.:||.|        |
 Worm    58 GDWTKEYGPMYGFTDGVEKTLVVSDPEFVHEVFVKQFDNFYAR------KQNPLQGDPDKDPRIH 116

  Fly   118 LFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCG-ILEIGDLMARY 181
            |....|.:|:.||...||||::..::.:|.|   |.|.:.::...|......| .::|.:....:
 Worm   117 LVTSQGHRWKRLRTLASPTFSNKSLRKIFST---VEESVAEMMRHLEKGTAGGKTIDILEYYQEF 178

  Fly   182 TSDVIGRCAFGVECNGL-RNPEAE-------------FAIMG---------RRAFSERRHCKLVD 223
            |.|:||:.|.|...:.: .||..:             |.|.|         |..||:....:.|.
 Worm   179 TMDIIGKIAMGQSGSMMFENPWLDKIRAIFNTRGNIIFIICGIVPFTGSIFRWFFSKVPTAQTVT 243

  Fly   224 GFIESFPEVARFLRMRQ-------------IHQDITDFYVGIVRET--VKQREEQGIVRSDFMNL 273
            ..:.:. |:|...|:.|             ..||..|.::.:..:|  ::...:.|..||..
 Worm   244 SLMHTL-EIALTKRVEQRAADEKAGIESSGEPQDFIDLFLDVQADTDFLEDETKNGFARSQI--- 304

  Fly   274 LIEMKQRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGE 338
               :|....||.:|:..|.|:|..||:||:|.:|.::.|.||:.|.:|.||:||:|:  ...:.|
 Worm   305 ---VKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDR--ECPDPE 364

  Fly   339 FTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDR--HFYIEPGQMLLIPVYGIHHD 401
            .|:|.:.:|:|||.||.||||.||    |..|..:....|...  ...||.|..:....:.:|:|
 Worm   365 VTFDQLSKLKYMECVIKETLRLYP----LASIVHNRKCMKSTTVLGMKIEEGTNVQADTWTLHYD 425

  Fly   402 PALYPE-PHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVC 465
            |..:.| .::|.|||:.:.........|:||||.|||.|||||...|:..:.|..:|:.:.....
 Worm   426 PKFWGENANEFKPERWESGDEQAVAKGAYLPFGLGPRICIGMRLAYMEEKMLLAQILKKYSLETT 490

  Fly   466 PRTDPKIEFLKSNILLCPANGIYLKVQ 492
            ..|...::.:  .|.......::||::
 Worm   491 FETHIPLKLV--GIATTAPTNVHLKLK 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	134/515 (26%)
cyp-13A3	NP_496110.1	p450	33..512	CDD:278495	133/514 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I2666
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.880