Protein Alignment Cyp6a22 and cyp-13A8

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_496115.1
• Gene: cyp-13A8 / 188358
• WormBaseID: WBGene00011674
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 537
• Identity: 142/537 - (26%)
• Similarity: 239/537 - (44%)
• Gaps: 112/537 - (20%)

  Fly     4 VVALLLIALAV-GFWFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPIY--EKFKG 65
            :..|:||::.. .||    .:::|.|||:.. |...|:....|......|    .|.|  :|:..
 Worm     2 IFELILISIVTYYFW----HWTFWKRRGLPG-PWGVPIFGKAGAMLEDSF----PPGYTLQKWTK 57

  Fly    66 NGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTG--------HLFRID 122
            ......||...::.|::::|.:|.::||::.:.||  .|..||    |:.|        |:....
 Worm    58 EYGKIYGFTEGMQKVMVISDPDLVQEILVKQYDNF--YGRKHN----PVQGDPDKDKDIHIVGAQ 116

  Fly   123 GPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDVIG 187
            |.:|:.||...:|.|::..:|.:..|:.:..:||.:...|.::|.....:.:  ....||.|||.
 Worm   117 GFRWKRLRTITAPAFSNGSIKKVLTTMEDSTQELMKKLREESENGKAVNMHL--FYQEYTFDVIS 179

  Fly   188 RCAFG-VECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIE-----------SFPEVARFLR--- 237
            |.|.| .:....:||                ..|.|.||.|           .||....||:
 Worm   180 RVAMGQPDSQMFKNP----------------LLKDVKGFFEHNRWQIWMFSGGFPFAVSFLKWLF 228

  Fly   238 ----------MRQIHQDITDFYVGIVRETVKQRE---EQGIVRSD-------FMNLLIEMKQRGE 282
                      ...:.:.:||    .|...:.|||   :.|:...:       |:|...|::..||
 Worm   229 IKVGKFGAGPFIVVQKSVTD----AVMSRIAQREADKKHGVEPGEAADYIDMFLNARAEVEHFGE 289

  Fly   283 ---------------LTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQAL 332
                           ||.:|:.:|.|:|..|||||:|.:|.:..|.||..|.:|:||::|:|:
 Worm   290 SNDEFHKSSSYNNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEVDK-- 352

  Fly   333 RLHNGEFTYDSMQELRYMELVIAETLRKYPI--LPQLTRISRHLYAAKGDRHFYIEPGQMLLIPV 395
            ...|.|.|:|.:.:|:||:.||.|:||.:|.  .....|..|:  ...|::  .:|.|..::|..
 Worm   353 ECPNDEITFDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRN--TVIGEQ--IVEAGVDVMIDT 413

  Fly   396 YGIHHDPALY-PEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVS-LLR 458
            :.:|||..:: .:..:|.|||:   .....|..|:|.||.|||.|:||||..::.. ||:| :|:
 Worm   414 WTLHHDKNVWGNDVEEFKPERW---DSPLTPQQAYLSFGAGPRVCLGMRFALLEQK-GLLSHILK 474

  Fly   459 NFHFSVCPRTDPKIEFL 475
            .:.|....:|...|:.:
 Worm   475 KYTFETNAKTQLPIKLV 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	133/505 (26%)
cyp-13A8	NP_496115.1	p450	27..503	CDD:278495	133/508 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.830