Protein Alignment Cyp6a22 and cyp-13A8

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_496115.1
• Gene: cyp-13A8 / 188358
• WormBaseID: WBGene00011674
• Length: 509
• Species: Caenorhabditis elegans
• Alignment Length: 537
• Identity: 142/537 - (26%)
• Similarity: 239/537 - (44%)
• Gaps: 112/537 - (20%)

  Fly     4 VVALLLIALAV-GFWFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPIY--EKFKG 65
            :..|:||::.. .||    .:::|.|||:.. |...|:....|......|    .|.|  :|:..
 Worm     2 IFELILISIVTYYFW----HWTFWKRRGLPG-PWGVPIFGKAGAMLEDSF----PPGYTLQKWTK 57

  Fly    66 NGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTG--------HLFRID 122
            ......||...::.|::::|.:|.::||::.:.||  .|..||    |:.|        |:....
 Worm    58 EYGKIYGFTEGMQKVMVISDPDLVQEILVKQYDNF--YGRKHN----PVQGDPDKDKDIHIVGAQ 116

  Fly   123 GPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDVIG 187
            |.:|:.||...:|.|::..:|.:..|:.:..:||.:...|.::|.....:.:  ....||.|||.
 Worm   117 GFRWKRLRTITAPAFSNGSIKKVLTTMEDSTQELMKKLREESENGKAVNMHL--FYQEYTFDVIS 179

  Fly   188 RCAFG-VECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIE-----------SFPEVARFLR--- 237
            |.|.| .:....:||                ..|.|.||.|           .||....||:
 Worm   180 RVAMGQPDSQMFKNP----------------LLKDVKGFFEHNRWQIWMFSGGFPFAVSFLKWLF 228

  Fly   238 ----------MRQIHQDITDFYVGIVRETVKQRE---EQGIVRSD-------FMNLLIEMKQRGE 282
                      ...:.:.:||    .|...:.|||   :.|:...:       |:|...|::..||
 Worm   229 IKVGKFGAGPFIVVQKSVTD----AVMSRIAQREADKKHGVEPGEAADYIDMFLNARAEVEHFGE 289

  Fly   283 ---------------LTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQAL 332
                           ||.:|:.:|.|:|..|||||:|.:|.:..|.||..|.:|:||::|:|:
 Worm   290 SNDEFHKSSSYNNRQLTTQEIISQCFVFLVAGFDTTAISLSYVTYFLALNPKIQSKLQDEVDK-- 352

  Fly   333 RLHNGEFTYDSMQELRYMELVIAETLRKYPI--LPQLTRISRHLYAAKGDRHFYIEPGQMLLIPV 395
            ...|.|.|:|.:.:|:||:.||.|:||.:|.  .....|..|:  ...|::  .:|.|..::|..
 Worm   353 ECPNDEITFDQLSKLKYMDNVIKESLRLFPFASFANSRRCMRN--TVIGEQ--IVEAGVDVMIDT 413

  Fly   396 YGIHHDPALY-PEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVS-LLR 458
            :.:|||..:: .:..:|.|||:   .....|..|:|.||.|||.|:||||..::.. ||:| :|:
 Worm   414 WTLHHDKNVWGNDVEEFKPERW---DSPLTPQQAYLSFGAGPRVCLGMRFALLEQK-GLLSHILK 474

  Fly   459 NFHFSVCPRTDPKIEFL 475
            .:.|....:|...|:.:
 Worm   475 KYTFETNAKTQLPIKLV 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	126/472 (27%)
cyp-13A8	NP_496115.1	CYP3A-like	58..500	CDD:410678	126/472 (27%)