Protein Alignment Cyp6a22 and cyp-13A5

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_496112.1
• Gene: cyp-13A5 / 188356
• WormBaseID: WBGene00011672
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 530
• Identity: 148/530 - (27%)
• Similarity: 238/530 - (44%)
• Gaps: 85/530 - (16%)

  Fly     5 VALLLIALAVGFWFVRTRY----SYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTP----IYE 61
            ::|.::.....|..:.|.|    |:|.|:|: ..|..||.     |.....|.|...|    :.|
 Worm     1 MSLSILIAGASFIGLLTYYIWIWSFWIRKGV-KGPRGFPF-----FGVIHEFQDYENPGLLKLGE 59

  Fly    62 KFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTG--------HL 118
            ..|..| |..|....:...::|::.|...::.::.|.||      :..:.:|:.|        ||
 Worm    60 WTKEYG-PIYGITEGVEKTLIVSNPEFVHEVFVKQFDNF------YGRKTNPIQGDPNKNKRAHL 117

  Fly   119 FRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCG-ILEIGDLMARYT 182
            ....|.:|:.||...||||::..::.:..||.|...||.:   .|.|.:..| .:::.|....:|
 Worm   118 VSAQGHRWKRLRTLSSPTFSNKNLRKIMSTVEETVVELMR---HLDDASAKGKAVDLLDYYQEFT 179

  Fly   183 SDVIGRCAFG-VECNGLRNPEAEFAIMGRRAFSERRHCK-LVDGFIESFPEVAR-----FLRMRQ 240
            .|:|||.|.| .|....|||... .:.|  .|.:.|... ||.|.   ||....     |:|...
 Worm   180 LDIIGRIAMGQTESLMFRNPMLP-KVKG--IFKDGRKLPFLVSGI---FPIAGTMFREFFMRFPS 238

  Fly   241 IHQ--DITDFYVGIVRETVKQR---EEQGIVRS----DFMNLLIE-------------------- 276
            |..  ||.......:.:.::||   |:.||..|    ||::|.::
 Worm   239 IQPAFDIMSTVEKALNKRLEQRAADEKAGIEPSGEPQDFIDLFLDARANVDFFEEESALGFAKTE 303

  Fly   277 -MKQRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFT 340
             .|...:||.:|:..|.|:|..||:||:|.:|.::.|.||:.|.:|.||:||:|:  ...|.|.|
 Worm   304 IAKVDKQLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDR--ECPNPEVT 366

  Fly   341 YDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDR--HFYIEPGQMLLIPVYGIHHDPA 403
            :|.:.:|:|||.|:.|.||.||    |..|..:....|...  ...||.|..:.:..:.:|:||.
 Worm   367 FDQISKLKYMECVVKEALRMYP----LASIVHNRKCMKETNVLGVQIEKGTNVQVDTWTLHYDPK 427

  Fly   404 LYPE-PHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPR 467
            ::.| .::|.|||:.:..........:||||.|||.|||||...|:..:.|..:|:.:.|....:
 Worm   428 VWGEDANEFRPERWESGDELFYAKGGYLPFGMGPRICIGMRLAMMEKKMLLTHILKKYTFETSTQ 492

  Fly   468 TDPKIEFLKS 477
            |:..::.:.|
 Worm   493 TEIPLKLVGS 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	140/496 (28%)
cyp-13A5	NP_496112.1	p450	33..514	CDD:278495	140/497 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I2666
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.880