Protein Alignment Cyp6a22 and cyp-13A4

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_496111.1
• Gene: cyp-13A4 / 188355
• WormBaseID: WBGene00011671
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 153/548 - (27%)
• Similarity: 247/548 - (45%)
• Gaps: 102/548 - (18%)

  Fly     8 LLI--ALAVGF-----WFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTP----IYE 61
            |||  ||.:||     |.    :|:|.|:|: ..|..||.     |.....|.|...|    :.|
 Worm     5 LLIAGALFIGFLTYYIWI----WSFWIRKGV-KGPRGFPF-----FGVILKFHDYENPGLLKLGE 59

  Fly    62 KFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTG--------HL 118
            ..|..|:.: |....:...::|::.|...::.::.|.||      :..:.:|:.|        ||
 Worm    60 WTKKYGSIY-GITEGVEKTLVVSNPEFVHEVFVKQFDNF------YGRKTNPIQGDPNKNKRAHL 117

  Fly   119 FRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTS 183
            ....|.:|:.||...||||::..::.:..||.|...||.:...|.  :|....:::.|....:|.
 Worm   118 VLAQGHRWKRLRTLASPTFSNKSLRKIMSTVEETVVELMRHLDEA--SAKGKAVDLLDYYQEFTL 180

  Fly   184 DVIGRCAFG-VECNGLRNP-----EAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIH 242
            |:|||.|.| .|....|||     :..|...|:..|       |:.|.   || :|..| |||:.
 Worm   181 DIIGRIAMGQTESLMFRNPMLPKVKEIFKKGGKMPF-------LIAGV---FP-IAGTL-MRQLF 233

  Fly   243 QDITDF-----YVGIVRETVKQREEQ-------GIVRS----DFMNLLIE--------------- 276
            .....|     .:..:.:.:.:|.||       ||..|    ||::|.::
 Worm   234 MKFPKFSPAFGIMNTMEKALNKRLEQRAADKKAGIEPSGEPQDFIDLFLDARANVDFIEEESTLG 298

  Fly   277 ------MKQRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLH 335
                  :|....||.:|:..|.|:|..||:||:|.:|.::.|.||..|.:|.||:||:|:  ...
 Worm   299 FAKSEVLKVDKHLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLATHPEIQKKLQEEVDR--ECP 361

  Fly   336 NGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHH 400
            :.|.|:|.:.:|:|||.|:.|.||.|| |..|.. :|............|:.|..:.:..:.:|:
 Worm   362 DPEVTFDQISKLKYMECVVKEALRMYP-LASLVH-NRKCMKKTNVLGVEIDEGTNVQVDTWTLHY 424

  Fly   401 DPALY-PEPHKFIPERF-LADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFS 463
            ||.:: .:..:|.|||: ..|:|.. ....:||||.|||.|||||...|:..:.|..:|:.:.|.
 Worm   425 DPKVWGDDASEFKPERWETGDELFY-AKGGYLPFGMGPRICIGMRLAMMEEKLLLTHILKKYTFD 488

  Fly   464 VCPRTDPKIEFLKSNILLCPANGIYLKV 491
            ....|:..:: |..:..:.|.| :.||:
 Worm   489 TSTETEIPLK-LVGSATIAPRN-VMLKL 514

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	140/512 (27%)
cyp-13A4	NP_496111.1	p450	33..514	CDD:278495	140/513 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	180	1.000	Inparanoid score	I2666
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.880