Protein Alignment Cyp6a22 and cyp-13B2

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_510369.2
• Gene: cyp-13B2 / 187068
• WormBaseID: WBGene00010606
• Length: 511
• Species: Caenorhabditis elegans
• Alignment Length: 541
• Identity: 147/541 - (27%)
• Similarity: 242/541 - (44%)
• Gaps: 121/541 - (22%)

  Fly     2 LDVVALLLIALAVGFWFVRTRYSYWTRRGIGSEPARFPVG--------NMEGFRKNKHFIDIVTP 58
            :.|:..|:..:.|...:.:..:|||.||||..     |||        ::....|.:.||
 Worm     1 MGVIVCLVAIIGVVAGYFKWIHSYWKRRGIEG-----PVGLPFIGSFYDLADREKPRGFI----- 55

  Fly    59 IYEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDR-------GMYHNERDDPLTG 116
            |.:..|..|..| |::..:.||::|:||::.:::.|:.|..|..|       |.....:::|..
 Worm    56 INKWTKMFGKVF-GYYEGVIPVLVVSDLDMLQEMFIKKFDCFYARKTTNLIHGNLECSQEEPRV- 118

  Fly   117 HLFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCE-----VGEELTQVCGELADNAMCGILEIGD 176
            :||...|.:|:.||...||.|:...:|.:..|:.:     |.....||.||        ...|.:
 Worm   119 NLFAARGARWKRLRALASPAFSVKALKQIHETMEDSVFSMVDHMSKQVNGE--------AFNIHE 175

  Fly   177 LMARYTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQI 241
            ....:|.|||.|.|.|                  :.:||:.:.:.|| .::..     |||..::
 Worm   176 YYQEFTYDVISRLAMG------------------QTYSEQFNNEGVD-IVKKI-----FLRKNRV 216

  Fly   242 ----------------------HQDITDFYVG--------IVRETVKQRE---EQGI--VRSDFM 271
                                  |:.:....||        .|.:.:|:|.   ||||  ..:||:
 Worm   217 YPWYLAVMFPGFENTIKNTFFNHEAVRGGDVGKLLKFCETAVHDRLKERADNVEQGIENPHNDFI 281

  Fly   272 NLLIE-------------MKQRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAK 323
            ::.::             :|...::|.|::....|:|..|||||:|:||.:|.|.|||.|....|
 Worm   282 DMFLDYYTDTNIEDNAFGIKVEKKVTSEDVIGACFVFLLAGFDTTANTLAYASYLLAKHPQEMRK 346

  Fly   324 LREEIDQALRLHNGE-FTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEP 387
            :::|||   |:...| .:||.:.:||||:.||.|.||.||:  .....||....|....::|||.
 Worm   347 VQDEID---RICTSEHISYDDIGKLRYMDAVIREALRMYPV--AWFACSRECVQATTLGNYYIEK 406

  Fly   388 GQMLLIPVYGIHHDPALY-PEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTI 451
            |..:...|..:|:...:: ...::|:|||:|  :.:.|...:|:|||.|||.|:|||.|..:...
 Worm   407 GVRIEADVRALHYSEEIWGKNANEFVPERWL--ESSPRHNMSWIPFGAGPRQCVGMRLGLSEAKT 469

  Fly   452 GLVSLLRNFHFSVCPRTDPKI 472
            .|..|||.|.....|:|:.::
 Worm   470 ALAHLLRRFSILAGPKTEKEL 490

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	129/469 (28%)
cyp-13B2	NP_510369.2	CYP3A-like	62..505	CDD:410678	129/470 (27%)