DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a22 and cyp-25A6

DIOPT Version :9

Sequence 1:	NP_001286431.1	Gene:	Cyp6a22 / 49847	FlyBaseID:	FBgn0013773	Length:	499	Species:	Drosophila melanogaster
Sequence 2:	NP_001360017.1	Gene:	cyp-25A6 / 187059	WormBaseID:	WBGene00019438	Length:	235	Species:	Caenorhabditis elegans

Alignment Length:	230	Identity:	60/230 - (26%)
Similarity:	106/230 - (46%)	Gaps:	23/230 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VVALLLIALAVGF--WFVRTRYSYWTRRG----IGSEPARFPVGNMEGF--RKNKHFIDIVTPIY 60
            ::..:|::| |.|  :.:..|...:..||    .|.|| .:.:||::..  ||.|...|.....|
Worm     5 ILTSILVSL-VSFIIYVILARKERFRLRGKIGLSGPEP-HWLMGNLKQIIERKAKLGYDDSYDWY 67

  Fly    61 EKF-KGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRG----MYHNERDDPLTGHLFR 120
            .|. |..|..| |.:...:..:.:|:.|..|::.|::|:||.||.    :..|:..:.|..:.:.
Worm    68 NKLHKQFGETF-GIYFGTQLNINITNEEDIKEVFIKNFSNFSDRTPPPIIEDNKLKESLLQNTYE 131

  Fly   121 IDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDV 185
               ..|:..|..::|.|::.|||.|..|:....:...::..|.|.:..  ..:|.|.....|.||
Worm   132 ---SGWKHTRSAIAPIFSTGKMKAMHETIHSKVDLFLEILKEKASSGQ--KWDIYDDFQGLTLDV 191

  Fly   186 IGRCAFGVECNGLRNPEAEFAIMGRRAFS--ERRH 218
            ||:|||.::.|..|:....|.:..|:..:  :.||
Worm   192 IGKCAFAIDSNCQRDRNDIFYVNARKFITNIDIRH 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	51/193 (26%)
cyp-25A6	NP_001360017.1	p450	37..>215	CDD:386267	50/184 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.820