Protein Alignment Cyp6a22 and cyp-13A12

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_499705.1
• Gene: cyp-13A12 / 184473
• WormBaseID: WBGene00008810
• Length: 518
• Species: Caenorhabditis elegans
• Alignment Length: 522
• Identity: 148/522 - (28%)
• Similarity: 243/522 - (46%)
• Gaps: 72/522 - (13%)

  Fly     4 VVALLLIALAVG-FWFVRTRYSYWTRRGIGSEPARFPVGNMEGFRKNKHFIDIVTPIY----EKF 63
            ::.|.::...:| ..|....:|||.||||.. |:.:|:     .......:....|.|    |..
 Worm     3 IIFLAILTSIIGVLSFYLWTWSYWKRRGIAG-PSGYPI-----LGSALEMLSSENPPYLQLKEWT 61

  Fly    64 KGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTG--------HLFR 120
            |..|..: |....|...::::|.:|.:::.::.:.||..|.:      :|:.|        :||.
 Worm    62 KQYGKVY-GITEGLSRTLVISDPDLVQEVFVKQYDNFFGRKL------NPIQGDPNKDKRVNLFS 119

  Fly   121 IDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDV 185
            ..|.:|:.||...||||::..::.:..||.|...||.:...:..|...  .:::.|....:|.||
 Worm   120 SQGHRWKRLRTISSPTFSNNSLRKLKTTVEECAVELLRHIEQHTDGGQ--PIDLLDFYQEFTLDV 182

  Fly   186 IGRCAFG-VECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLR--MRQIHQDITD 247
            |||.|.| .:....:||...:.   |..|.|.|....:.|.:.  |.:...||  |..:...:.:
 Worm   183 IGRIAMGQTDSQMFKNPLLPYV---RAVFGEPRKGLFLSGSLA--PWIGPILRMVMFSLPNIVKN 242

  Fly   248 FYVGIVRET---VKQR-------EEQGI---VRSDFMNLLIE------------------MKQRG 281
            ..|.::|.|   |:||       |:.||   ...||::|.::                  :|...
 Worm   243 PAVHVIRHTSNAVEQRVKLRMADEKAGIDPGEPQDFIDLFLDAKSDDVELENNEDFTKAGVKVTR 307

  Fly   282 ELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQE 346
            :||.||:..|.|:|..|||||:|.:|.::.:.||..|.:|.||:||||:  ...:.|.|:|.:.:
 Worm   308 QLTTEEIVGQCFVFLIAGFDTTALSLSYSSFLLATHPKVQKKLQEEIDR--ECADPEVTFDQLSK 370

  Fly   347 LRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPE-PHK 410
            |:|||.||.||||.|| |..|.. ||....|....::.|:.|..:|...:.:|.|.:::.| ..:
 Worm   371 LKYMECVIKETLRMYP-LGALAN-SRCCMRATKIGNYEIDEGTNILCDTWTLHSDKSIWGEDAEE 433

  Fly   411 FIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFL 475
            |.|||:.:..........::|||.|||.|||||...|:..:.|..:||.:...||.:|...::.:
 Worm   434 FKPERWESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHILRKYTLEVCNKTQIPLKLI 498

  Fly   476 KS 477
            .|
 Worm   499 GS 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	138/490 (28%)
cyp-13A12	NP_499705.1	p450	33..507	CDD:278495	138/492 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.830