Protein Alignment Cyp6a22 and cyp-13A11

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_499704.1
• Gene: cyp-13A11 / 184472
• WormBaseID: WBGene00008809
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 540
• Identity: 149/540 - (27%)
• Similarity: 251/540 - (46%)
• Gaps: 108/540 - (20%)

  Fly     4 VVALLLIALAVG-----FWFVRTRYSYWTRRGIGSEPARFP-VGN----MEGFRKNKHFIDIV-- 56
            ::.|.:::..||     ||    .::||.|.||.. |..:| :|:    |:  .:|..|:.:.
 Worm     2 IILLFVVSSVVGIVSYYFW----TWTYWRRCGIPG-PQGYPFLGSALDMMD--HENPPFLQLKKW 59

  Fly    57 TPIYEKFKG--NGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGH-- 117
            |..|.|..|  .|        :||.:| ::|..|..::.::.:.||..|.:      :|:.|.
 Worm    60 TSQYGKVYGITEG--------LLRTLV-ISDTNLIHEVFVKQYDNFYGRNL------NPIQGDPN 109

  Fly   118 ------LFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCG-ILEIG 175
                  ||...|.:|:.||...:|||:|..::.:..||.:...||.:   .:..:...| .:::.
 Worm   110 REKRVTLFSAQGHRWKRLRTIANPTFSSNNLRKIQVTVEDSALELLR---HIEQHTAGGKAIDVL 171

  Fly   176 DLMARYTSDVIGRCAFGVECNGL--RNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRM 238
            :....:|.|||||.|.| :.:.|  :||....|   |..|.:.|....:.|.:  ||.:...:|
 Worm   172 EYFQEFTMDVIGRIAMG-QPDSLMFKNPLLPCA---RDVFGKPRTALFLSGIL--FPWIGPMIR- 229

  Fly   239 RQIHQDITDFYVGI---------------VRETVKQR---EEQGI---VRSDFMNLLIE------ 276
                 .:..::..:               |.:.:|||   |:.||   ...||::|.::
 Worm   230 -----KVVFYFTNVFNNPAAQIMYQTANAVEQRIKQRMAEEKAGIDPGEPQDFIDLFLDAKSDDM 289

  Fly   277 ------------MKQRGELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEID 329
                        :|...:||.:|:..|.|:|..|||||:|.:|.::.:.||..|..|.||:||||
 Worm   290 ELENNEDFTKAGVKVTRQLTKDEVVGQCFVFLIAGFDTTALSLSYSSFLLATHPKAQKKLQEEID 354

  Fly   330 QALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAK-GDRHFYIEPGQMLLI 393
            :  ...:.|.|:|.:.:|:|||.||.||||.|| |..|....|.:.:.| |  ::.||.|..:|.
 Worm   355 R--ECADPEVTFDQLSKLKYMECVIKETLRMYP-LGALANSRRCMRSTKIG--NYEIEKGVDILC 414

  Fly   394 PVYGIHHDPALYPE-PHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLL 457
            ..:.:|:|.:::.| ..:|.|||:.:..........::|||.|||.|||||...|:..:.|..:|
 Worm   415 DTWTLHYDKSIWGEDAEEFKPERWESGDEHFYQKGGYIPFGLGPRQCIGMRLAYMEEKLLLSHIL 479

  Fly   458 RNFHFSVCPRTDPKIEFLKS 477
            |.:...||.:|...::.:.|
 Worm   480 RKYTLEVCNKTQIPLKLIGS 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	139/504 (28%)
cyp-13A11	NP_499704.1	p450	31..506	CDD:278495	139/507 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	171	1.000	Domainoid score	I2249
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.830