Protein Alignment Cyp6a22 and cyp-25A4

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_497779.1
• Gene: cyp-25A4 / 183248
• WormBaseID: WBGene00007967
• Length: 501
• Species: Caenorhabditis elegans
• Alignment Length: 528
• Identity: 142/528 - (26%)
• Similarity: 245/528 - (46%)
• Gaps: 70/528 - (13%)

  Fly     5 VALLLIALAVGFWFVRT--RYSYWTRR---------GIGSEPARFPVGNME---------GFRKN 49
            :|:|:|:..  |:.:.|  .||.|.|.         ||...|..:..||:.         |:...
 Worm     1 MAILIISTI--FFTIITFISYSIWRRHAIFKLRSSIGIPGPPVHWLWGNLNIIKDRVSRLGYNDT 63

  Fly    50 KHFIDIVTPIYEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDR------GMYHN 108
            ..:...:...|       .|..|.:...:..:.|::.|..|:|.||:|:||.||      ||  |
 Worm    64 TQWHPTLHTKY-------GPIFGLYCGTQLHITVSEEEDIKEIFIQNFSNFSDRMTPDIFGM--N 119

  Fly   109 ERDDPLTGHLFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILE 173
            :.:..|..:.:   ...|:..|..::|.|::.|||.|..|:....:...:|..|.:.:.     :
 Worm   120 QLNQSLLQNTY---ATGWKHTRSAIAPIFSTGKMKAMHETLVSKIDIFLEVLKEKSSSG-----Q 176

  Fly   174 IGDLMARYTS---DVIGRCAFGVECNGLRNPEAEFAIMGRR---AFSERRHCKLVDGFIESFPEV 232
            ..|:...:.|   |:||:|||.::.|..|:....|.:..|:   |...::...|....|  .||:
 Worm   177 KWDIFENFQSLSLDIIGKCAFAIDSNCQRDRTDLFYVQARKFVGAVDLKKSWILPVSLI--LPEL 239

  Fly   233 ARFLRMRQIHQDITDFYVGIVRETV-----KQREEQGIVRSDFMNLLIEMKQRGELTIEEMAAQA 292
            :...|......|::...:.:|:..|     ::..|.|...:|.:||||..:..|::|..|:....
 Worm   240 SWLWRFLYKFSDLSAAELPLVKGLVDLYDRRRAGEGGNDSTDLLNLLIRRETIGKMTQREVIENC 304

  Fly   293 FIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAET 357
            |.|..||::|:::.:.|:.|.||:.|.:|.||.|||.:.  ..|....|||:..::|::.|..|:
 Worm   305 FAFLIAGYETTSTAMMFSAYLLAEYPIVQQKLYEEIKKT--KENAGLNYDSIHNMKYLDCVYKES 367

  Fly   358 LRKYPILPQLT-RISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQL 421
            ||.||.....| |:..:....:|  ..|.|...:.:.| |.||.:||.:..|.:|.||||  :..
 Worm   368 LRFYPPTTHFTNRVCLNDMTIRG--QIYPEDSTLKVQP-YTIHRNPANWESPDEFQPERF--ENW 427

  Fly   422 AQRPTA-AWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSN-ILLCPA 484
            .::.:: .|:|||.|||.|:||||.:|:....:..||..|..|:.|...|.|.  ::| ::..|.
 Worm   428 EEKSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTFELSLVPGDPPMIP--ETNGVIFRPR 490

  Fly   485 NGIYLKVQ 492
            :.:.|.::
 Worm   491 SPVRLNLK 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	125/441 (28%)
cyp-25A4	NP_497779.1	CYP3A-like	73..494	CDD:410678	126/448 (28%)