Protein Alignment Cyp6a22 and cyp-13B1

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_510233.1
• Gene: cyp-13B1 / 181462
• WormBaseID: WBGene00008519
• Length: 510
• Species: Caenorhabditis elegans
• Alignment Length: 550
• Identity: 153/550 - (27%)
• Similarity: 248/550 - (45%)
• Gaps: 110/550 - (20%)

  Fly     4 VVALLLIALAVGF--WFVRTRYSYWTRRGIGSEPARFP-VGN---MEGFRKNKHFIDIVTPIYEK 62
            :|.::|.|...|:  |.    ::||.|||| |.|...| :||   :....|.:.:  ::....:|
 Worm     5 IVLVVLFATIAGYFKWI----HTYWRRRGI-SGPEGLPFIGNYYDLADVNKPRGY--LIHKWTQK 62

  Fly    63 FKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDR-------GMYHNERDDPLTGHLFR 120
            |   |..| |::....||::|:|:::.:::.::.|.||..|       |.....:.:|.. :||.
 Worm    63 F---GKVF-GYYEGAVPVLVVSDMDMLQELFLKKFDNFYARKSTNHIHGNLECSKSEPRI-NLFT 122

  Fly   121 IDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMAR----- 180
            ..|.:|:.||...||.|:...:|              ||...:.|:|    :.:.||||:
 Worm   123 SRGARWKRLRALASPGFSVKALK--------------QVHDVMEDSA----INMVDLMAKHEDGK 169

  Fly   181 ----------YTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARF 235
                      :|.|||.|.|.|...:.|.|......:   ::...|.|..|...|...||:....
 Worm   170 PFNIHAYFQEFTYDVISRLAMGQPNSELFNNSGVEIV---KSIFMRTHRVLPWYFTVLFPQFEHL 231

  Fly   236 L-RMRQIHQ-----DITDFYVGIVRETV----KQREEQGIV-----RSDFMNLL-------IEMK 278
            : ||...|.     ||....: |.::||    ::|||...:     .:||:::.       :|..
 Worm   232 VKRMFYNHAAVQGGDIEKLLL-ICKKTVESRIQEREENAKLGFENAENDFIDMFLNYYSEQVEDI 295

  Fly   279 QRG-----ELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGE 338
            :.|     ::|.|::....|:|..|||||:|::|.:|.|.|||.|......:||:|..:...|
 Worm   296 EFGSTVEKKVTAEDVIGACFVFLLAGFDTTANSLAYASYLLAKHPEKMKLAQEEVDTVVGSEN-- 358

  Fly   339 FTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLY--AAKGDRHFYIEPGQMLLIPVYGIHHD 401
            .:||.|.:|:|::.|:.|:||.||:  .....||...  ...||  .||:.|..:...|..:|..
 Worm   359 VSYDDMTKLKYLDAVVRESLRLYPV--AWFACSRECVKPTTLGD--IYIDKGVKIEADVMSLHRS 419

  Fly   402 PALYPE-PHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVC 465
            ..::.| ...|:|||:|  :.:.|.|.:|:|||.|||.|:|||.|..:....|..|||.:.....
 Worm   420 KEIWGENADDFVPERWL--EPSSRHTMSWIPFGAGPRQCVGMRLGLSEAKTALAHLLRRYDLVAG 482

  Fly   466 PRTDPKIEFLKSNILLCPANG-----IYLK 490
            ..|:.::     |||.|....     :|||
 Worm   483 VETEKEL-----NILGCTTTSPEAVTLYLK 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	131/478 (27%)
cyp-13B1	NP_510233.1	CYP3A-like	62..500	CDD:410678	133/477 (28%)