Protein Alignment Cyp6a22 and cyp-25A2

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_497776.2
• Gene: cyp-25A2 / 175495
• WormBaseID: WBGene00007964
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 143/510 - (28%)
• Similarity: 243/510 - (47%)
• Gaps: 45/510 - (8%)

  Fly     1 MLDVVALLLIALAVGFWFVRTRYSYWTRRGI---GSEPARFPVGNMEGF--RKNKHFIDIVTPIY 60
            :|..:.:||::..:...|.| |..:..|..|   |.||..| :||::..  ||.|...|.....:
 Worm     5 ILTSILILLVSFIIYILFAR-REQFKLREKIGLTGPEPHWF-MGNLKQIVDRKEKLGYDDSNKWF 67

  Fly    61 -EKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGM----YHNERDDPLTGHLFR 120
             |..|..|..|..:|.....:||..:.:: |::.|::|:||.||.:    ..|:.:..|..:.:
 Worm    68 NELHKQYGETFGIYFGAQMNIVLSNEEDI-KEVFIKNFSNFSDRIVPPIFDSNQLNQSLLQNTY- 130

  Fly   121 IDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDV 185
              ...|:..|..::|.|::.|||.|..|:....:....:..|.|.:..  ..:|.:.....|.||
 Worm   131 --ATGWKHTRSAIAPIFSTGKMKAMQETIHSKVDLFLDILREKASSGQ--KWDIYEDFQGLTLDV 191

  Fly   186 IGRCAFGVECNGLRNPEAEFAIMGRR--AFSERRHCKLV-DGFIESFPEVARFLRMRQIHQDITD 247
            ||:|||.::.|..|:....|.:..|:  |..:.||.|:: ..||  .||:|...|....:..:.|
 Worm   192 IGKCAFAIDSNCQRDRNDVFYVNARKFIANIDIRHSKVIAASFI--LPELAPLWRALYKYTPLAD 254

  Fly   248 FYV----GIVRETVKQREEQGIVRSDFMNLLI--EMKQRGELTIEEMAAQAFIFFAAGFDTSAST 306
            ..:    |:.....::|..:|....|.:.||:  |..:...:|.:|:....|.|..||::|:::.
 Worm   255 AEIPLVEGLSNVYERRRGGEGSDSVDLLKLLLNREDDKSKPMTKQEVIENCFAFLLAGYETTSTA 319

  Fly   307 LGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKYPILPQLTRIS 371
            :.:..|.|:|.|.:|.||.|||.:|  ..||..||||:..::|::.|..||||.||  |.:..|:
 Worm   320 MTYCSYLLSKYPNVQQKLYEEIMEA--KENGGLTYDSIHNMKYLDYVYKETLRCYP--PVIHFIN 380

  Fly   372 RHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRPTA-AWLPFGDG 435
            |...|....|..:...|.::....:.:|.:|..:..|.:|.||||  :...::.:: .|:|||.|
 Worm   381 RRCLADITIRGQFYPKGSVVTCLPHTVHLNPENWDSPEEFHPERF--ENWEEKSSSLKWIPFGVG 443

  Fly   436 PRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPANGIYLK 490
            ||.|:||||.:|:....:|.||..|...         :|.....|:...||:.::
 Worm   444 PRYCVGMRFAEMEFKTTIVKLLDTFELK---------QFKGEADLIPDCNGVIMR 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	123/435 (28%)
cyp-25A2	NP_497776.2	CYP3A-like	73..495	CDD:410678	123/440 (28%)