Protein Alignment Cyp6a22 and Cyp3a62

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001019403.1
• Gene: Cyp3a62 / 170509
• RGDID: 1595919
• Length: 497
• Species: Rattus norvegicus
• Alignment Length: 521
• Identity: 157/521 - (30%)
• Similarity: 254/521 - (48%)
• Gaps: 69/521 - (13%)

  Fly     2 LDVVALLLIALAVGFWFVRTRYSYWTRRGI-GSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKG 65
            |:...||...|.:.:.:..:.:..:.:.|| |.:|..| |||:..:|..  |.:.....::|:
  Rat     9 LETWMLLATILVLLYLYGTSTHGNFKKLGISGPKPLPF-VGNILAYRHG--FWEFDRHCHKKY-- 68

  Fly    66 NGAPFAGFFMMLRPVVLVTDLELAKQILIQD-FANFEDRGMYHNERDDPLTGHLFRIDGP----- 124
              ....||:...:|::.:||.::.|.:|::: ::.|.:|                |..||
  Rat    69 --GDIWGFYEGRQPILAITDPDIIKTVLVKECYSTFTNR----------------RSFGPAGILK 115

  Fly   125 ---------KWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMAR 180
                     :|:.||..:||||||.|:|.|||.:.:..:.|.:.....|:..  ..:.:.|:...
  Rat   116 KAITLSEDEEWKRLRTLLSPTFTSGKLKEMFPIINQYADLLVKNVKHEAEKG--NPITMKDIFGA 178

  Fly   181 YTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLRMRQIHQ-- 243
            |:.|||...:|||..:.|.||:..|....::...    ...:|.|   |..|..|..:..:.:
  Rat   179 YSMDVITGTSFGVNVDSLNNPQNPFVQKVKKLLK----FNFLDPF---FLSVILFPFLTPVFEAF 236

  Fly   244 DITDFYVGIVR------ETVKQREEQGIV--RSDFMNLLIEMKQRGE------LTIEEMAAQAFI 294
            |||.|...:::      |.:|:...|..|  |.||:.|:|..:..|:      ||..|:.||:..
  Rat   237 DITVFPKDVMKFFRTSVERMKENRMQEKVKQRLDFLQLMINSQSSGDKESHQGLTDVEIVAQSIF 301

  Fly   295 FFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLR 359
            |..||::|::|.|.||||.||..|.||.||::|||.||. :....|||.:.|:.|:::|:.||||
  Rat   302 FIFAGYETTSSALSFALYLLATHPDLQKKLQDEIDAALP-NKAPVTYDVLVEMEYLDMVLNETLR 365

  Fly   360 KYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQR 424
            .:|:..:|.|:.:......|   .:|..|.::::|.:.:|.||..:|||.:|.||||........
  Rat   366 LFPVGGRLERVCKKDVEING---VFIPKGTVVMVPTFALHKDPKCWPEPEEFCPERFRKKNQDSI 427

  Fly   425 PTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPANGIYL 489
            ....:||||:||||||||||..|...|.||.:|:||.|.:|..|...::..|..... |...|.|
  Rat   428 NPYIYLPFGNGPRNCIGMRFALMNMKIALVRVLQNFSFGLCKETQIPLKLRKKGFFQ-PEKPIIL 491

  Fly   490 K 490
            :
  Rat   492 R 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	150/487 (31%)
Cyp3a62	NP_001019403.1	p450	39..491	CDD:278495	150/488 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	256	1.000	Domainoid score	I1960
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	274	1.000	Inparanoid score	I2893
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm8924
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.870