Protein Alignment Cyp6a22 and Cyp4a10

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 526
• Identity: 137/526 - (26%)
• Similarity: 234/526 - (44%)
• Gaps: 83/526 - (15%)

  Fly     7 LLLIALAVGFWFVRTRYSYWTRRG---IGSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKGNGA 68
            |||:..||.|:..|    .|..:.   ..|.|..:..|: |.|:.::...:||:.| |.|.   :
Mouse    28 LLLLVKAVQFYLHR----QWLLKAFQQFPSPPFHWFFGH-EKFKGDQELQEIVSCI-ENFP---S 83

  Fly    69 PFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFR------------I 121
            .|..:|...:..:.|.|.:..|.||               .|.||.....:|            :
Mouse    84 AFPRWFWGSKAYLTVYDPDYMKVIL---------------GRSDPKANGAYRLLAPWIGYGLLLL 133

  Fly   122 DGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGE---LADNAMCGILEIGDLMARYTS 183
            :|..|...|:.::|.|....:|   |.|..:.:.:..:..:   |||..  ..:||...::..|.
Mouse   134 NGQPWFQHRRMLTPAFHYDILK---PYVKNMADSIRLMLDKWERLADQD--SSIEIFQHISLMTL 193

  Fly   184 DVIGRCAF----GVECNGLRNPEAEFAIMG--RRAFSER-RHCKLVDGFIESFPEVARFLRMR-Q 240
            |.:.:|||    .|:.:|  |.......:|  ...|..| |:....:..|.......|..:.. |
Mouse   194 DTVMKCAFSHKGSVQVDG--NYRTYLQAIGDLNNLFHSRVRNIFHQNDTIYKLSSNGRLAKQACQ 256

  Fly   241 IHQDITDFYVGIVRETVKQREEQGIV-------RSDFMNLLI--EMKQRGELTIEEMAAQAFIFF 296
            :..|.||   |:::....|.:::|.:       |.||:::|:  .|:....::.:::.|:...|.
Mouse   257 LAHDHTD---GVIKLRKDQLQDEGELEKIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTFM 318

  Fly   297 AAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRKY 361
            ..|.||:||.:.:..|.||..|..|.:.|||: |:|.......|:|.:.::.|..:.|.|.||.|
Mouse   319 FEGHDTTASGVSWIFYALATHPDHQQRCREEV-QSLLGDGSSITWDHLDQIPYTTMCIKEALRLY 382

  Fly   362 PILPQLTR-ISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQRP 425
            |.:|.:.| :|..:....|..   :..|..:.:.:||:||:|.::|.|..|.|.||..|  :.|.
Mouse   383 PPVPGIVRELSTSVTFPDGRS---LPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPD--SPRH 442

  Fly   426 TAAWLPFGDGPRNCIGMRFGKMQ-TTIGLVSLLRNFHFSVCPRTDP-KIEFLKSNILLCPANGIY 488
            :.::|||..|.|||||.:|...: ..|..::|||   |.:.|  || ::....:.::|...||||
Mouse   443 SHSFLPFSGGARNCIGKQFAMSELKVIVALTLLR---FELLP--DPTRVPMPLARLVLKSKNGIY 502

  Fly   489 LKVQQL 494
            |.:::|
Mouse   503 LHLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	115/456 (25%)
Cyp4a10	NP_034141.3	CYP4B-like	71..504	CDD:410771	122/472 (26%)