Protein Alignment Cyp6a22 and Cyp3a11

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_031844.1
• Gene: Cyp3a11 / 13112
• MGIID: 88609
• Length: 504
• Species: Mus musculus
• Alignment Length: 537
• Identity: 160/537 - (29%)
• Similarity: 251/537 - (46%)
• Gaps: 98/537 - (18%)

  Fly     2 LDVVALLLIALAVGFWFVRTRYSYWTRRGI-GSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKG 65
            |:...||.|:|.:.:.:...::..:.::|| |.:|..| :|.:..:.|.....|:     |.:|.
Mouse     9 LETWVLLAISLVLLYRYGTRKHELFKKQGIPGPKPLPF-LGTVLNYYKGLWKFDM-----ECYKK 67

  Fly    66 NGAPFAGFFMMLRPVVLVTDLELAKQILIQD----FANFEDRG-------MYHNERDDPLTGHLF 119
            .|..: |.|....|::.|||.|..|.:|:::    |.|..|.|       .....:||
Mouse    68 YGKTW-GLFDGQTPLLAVTDPETIKNVLVKECFSVFTNRRDFGPVGIMSKAISISKDD------- 124

  Fly   120 RIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSD 184
                 :|:..|..:||||||.|:|.|||.:.:.|:.|.:...:.|....  .:.:.|::..|:.|
Mouse   125 -----EWKRYRALLSPTFTSGKLKEMFPVIEQYGDILVKYLRQKAKKGK--PVTMKDVLGAYSMD 182

  Fly   185 VIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARF-------------- 235
            ||...:|||..:.|.|||                    |.|:|...::.||
Mouse   183 VITSTSFGVNVDSLNNPE--------------------DPFVEKAKKLLRFDFFDPLLFSVVLFP 227

  Fly   236 --------LRMRQIHQDITDFYVGIV------RETVKQREEQGIVRSDFMNLLIEMKQRGE---- 282
                    |.:....:|..:|:...|      |...||:.     |.||:.|::......:
Mouse   228 FLTPVYEMLNICMFPKDSIEFFKKFVDRMKESRLDSKQKH-----RVDFLQLMMNSHNNSKDKVS 287

  Fly   283 ---LTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSM 344
               |:..|:.||:.||..||::|::|||.|.|:.||..|.:|.||::|||:||. :....|||::
Mouse   288 HKALSDMEITAQSIIFIFAGYETTSSTLSFTLHSLATHPDIQKKLQDEIDEALP-NKAPPTYDTV 351

  Fly   345 QELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPH 409
            .|:.|:::|:.||||.|||..:|.|:.:......|   .||..|..::||.|.:||||..:.||.
Mouse   352 MEMEYLDMVLNETLRLYPIANRLERVCKKDVELNG---VYIPKGSTVMIPSYALHHDPQHWSEPE 413

  Fly   410 KFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEF 474
            :|.||||..:.........:||||:|||||:||||..|...:.|..:::||.|..|..|...::.
Mouse   414 EFQPERFSKENKGSIDPYVYLPFGNGPRNCLGMRFALMNMKLALTKIMQNFSFQPCKETQIPLKL 478

  Fly   475 LKSNILLCPANGIYLKV 491
            .:.. ||.|...|.|||
Mouse   479 SRQG-LLQPEKPIVLKV 494

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	150/501 (30%)
Cyp3a11	NP_031844.1	p450	39..494	CDD:278495	151/505 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.820