Protein Alignment Cyp6a22 and LOC1281265

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_321208.6
• Gene: LOC1281265 / 1281265
• VectorBaseID: AGAMI1_014560
• Length: 505
• Species: Anopheles gambiae
• Alignment Length: 547
• Identity: 130/547 - (23%)
• Similarity: 237/547 - (43%)
• Gaps: 106/547 - (19%)

  Fly     4 VVALLLIA----LAVGFWFVRTRYSYWTRRGIGSEPARFP-VGNMEGFRKNKHFIDIVTPIYEK- 62
            ::..||||    |.:.....|.:.....:...|.:|  .| |||:..|.    ::|| ..::||
Mosquito     2 ILQALLIAGVVYLLISHLIERKKLQKINKHFPGPKP--LPVVGNLLQFA----WLDI-PGVFEKV 59

  Fly    63 ---FKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRIDGP 124
               .:.:|..:..:.:....::::|..:..:::|:   |...::.:.:...:..|...|....|.
Mosquito    60 VELHQTHGQDYMMWSLFNWTILMMTSRKNVEKVLL---AKQTEKALLYQFIEPWLGTGLLIASGE 121

  Fly   125 KWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGIL---------EIGDLMAR 180
            ||...|:.::|||.           .::.|:..:|.....| .|..:|         :|.|.:..
Mosquito   122 KWFQRRKIITPTFH-----------FKILEQFVRVFNTETD-TMVQLLRKHVGGKEFDIYDYVTL 174

  Fly   181 YTSDVIGRCAFGVECNGLRNPEAEF----------------AIMG----------RRAFSERRHC 219
            ...|.|...:.|...:...||:.::                :|:|          ..|:.:||..
Mosquito   175 MALDSICETSMGTTVDAQHNPDNQYVQNVKRMAVLVLLRTISIVGPYPTLYNLFHPNAWEQRRVI 239

  Fly   220 KLVDGFIESFPEVARFLRMRQIHQDITDFYVGIVRETVKQREEQGIV------------RSDFMN 272
            |.:..|.:|      .:|.|              ||.:.:.:.|.:.            :..|::
Mosquito   240 KQLHAFTDS------VIRSR--------------REQLAKEKAQNVAFDLNEENLYSKRKLTFLD 284

  Fly   273 LLIEMKQRGE-LTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQAL-RLH 335
            ||:.:...|: |:..::..:...|...|.||:.|.:.|.:||||:.|.:|.::.|||...| :.|
Mosquito   285 LLLNVTVEGKPLSNLDIREEVDTFMFEGHDTTTSGISFTIYELARNPDVQERVYEEIVSILGKDH 349

  Fly   336 -NGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIH 399
             ..|.||.::||.:|::||:.|.||.||.:..:.|.........|..   :..||.:|:|:|.||
Mosquito   350 KTAELTYQNLQEFKYLDLVVKEGLRMYPPVGIIGRALVEDLELNGTT---VPAGQNVLVPIYVIH 411

  Fly   400 HDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSV 464
            .:|.:||.|::|.|.||..|..::|....:|||..|.|||||.|:..|:..:.|:.|:.|:.  :
Mosquito   412 RNPEIYPNPNQFDPSRFAEDAESKRGPFDYLPFSIGARNCIGQRYALMEMKVTLIKLIANYR--I 474

  Fly   465 CPRTDPKIEFLKSNILLCPANGIYLKV 491
            .|........:|::::|.|..||.:|:
Mosquito   475 LPGESLGKLRVKTDLVLRPDIGIPVKI 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	111/471 (24%)
LOC1281265	XP_321208.6	None