Protein Alignment Cyp6a22 and LOC1280399

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_320246.5
• Gene: LOC1280399 / 1280399
• VectorBaseID: AGAMI1_004131
• Length: 549
• Species: Anopheles gambiae
• Alignment Length: 552
• Identity: 186/552 - (33%)
• Similarity: 273/552 - (49%)
• Gaps: 64/552 - (11%)

  Fly     2 LDVVAL-LLIALAVGFW-FVRTRYSYWTRRGIGSEPARFPVGN-----MEGFRKNKHFIDIVTPI 59
            :.||.| ||:.|.|..: :|...|.|:..:.|......||.||     |:.....:||.:    :
Mosquito     3 ISVVTLALLVGLCVAVYRYVTKNYFYFADKPIPFMKPSFPFGNAGPILMKKVTLFEHFKN----L 63

  Fly    60 YEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDR---GMYHNERDDP----LTGH 117
            |:.|.  .|...|.|.|.:||.:|.|.||.|||.::||..|.|.   ||...|.::.    |...
Mosquito    64 YDAFP--NARIHGTFNMRQPVYIVRDPELVKQITVKDFDYFVDHMTTGMEQTEDNNSNHLLLGNS 126

  Fly   118 LFRIDGPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCG-----ILEIGDL 177
            |..:.|.|||.:|..:||.||.:||:.||..:.:.|:.:.:...|....|...     .||:.|:
Mosquito   127 LVSLRGQKWRDMRATLSPAFTGSKMRLMFALIADCGKSMVEHFREEDKKARAAGGTGYQLEMKDV 191

  Fly   178 MARYTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESF-PEVARFLRMRQI 241
            |.|:.:||||..|||::.:..|:|...|..|.|...::....|::.....:| |::...|.:..:
Mosquito   192 MTRFANDVIGTAAFGIKVDSFRDPTNVFISMARSVTNQESLVKVLKMIGYTFAPKLMTRLNIDFL 256

  Fly   242 HQDITDFYVGIVRETVKQREEQGIVRSDFMNLLIEMKQ------------------RGELTIE-- 286
            ..:...|:...:.||::.|:|:||.|.|.:.||::.|:                  .|..|:|
Mosquito   257 TPEEDQFFRNTILETMRTRQEKGIFRPDMIELLMQAKKGSLKHQQAEEPRTDSETGEGFATVEES 321

  Fly   287 --------------EMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEI-DQALRLHN 336
                          |:.|||||||.|||:|.:.|:.|||||||....:||:|.||: |....|..
Mosquito   322 HVGRRAHDRVWTDTELIAQAFIFFFAGFETISWTISFALYELAVNEDIQARLYEEVRDAEQSLEE 386

  Fly   337 GE-FTYDSMQELRYMELVIAETLRKYPILPQLTR--ISRHLYAAKGDRHFYIEPGQMLLIPVYGI 398
            |: .||:.:|.|.|:::|::||||::||...|.|  :..:.|.......|.||.|.::.|||.||
Mosquito   387 GKTLTYEQLQSLPYLDMVVSETLRRWPIATVLNRECVRNYQYDDGQGTRFTIEKGTLVFIPVVGI 451

  Fly   399 HHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFS 463
            |.||..:|||.:|.||||.|..........:||||.|||||||.||..|:....|..||.||...
Mosquito   452 HFDPKYFPEPERFDPERFSAANRNNIQPGTYLPFGAGPRNCIGSRFALMEAKAALYYLLLNFRLV 516

  Fly   464 VCPRTDPKIEFLKSNILLCPANGIYLKVQQLS 495
            .|.:|...::..||:.......||:|:.|..|
Mosquito   517 PCAKTQIPLKLKKSSTQFATEQGIWLEFQSRS 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	162/472 (34%)
LOC1280399	XP_320246.5	None