Protein Alignment Cyp6a22 and LOC1277432

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_316781.2
• Gene: LOC1277432 / 1277432
• VectorBaseID: AGAMI1_006733
• Length: 531
• Species: Anopheles gambiae
• Alignment Length: 529
• Identity: 177/529 - (33%)
• Similarity: 271/529 - (51%)
• Gaps: 63/529 - (11%)

  Fly     7 LLLIALAVGFWFVRTRYS-YWTRRGIGSEPARFPVGNMEGFRKNKHFI-DIVTPIYEKFKGNGAP 69
            ||:..||:.:::|..|.: ::..||:...|....:||...|...|..: |:::.:|.:|..:  .
Mosquito    16 LLVALLALLYYYVVVRSTRFFADRGVPYLPPVPLLGNGADFITRKRLLTDVLSDMYHRFASH--R 78

  Fly    70 FAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGH-LFRIDGPKWRPLRQKM 133
            |.|:|..|.|:.:|.||||.|||.|:||.:|.:..:..:|..|||.|. ||.:...:||.:|..:
Mosquito    79 FFGYFDFLSPIYVVRDLELVKQICIKDFDHFVNHRIQLDENHDPLFGRALFAMRDTRWRNMRTIL 143

  Fly   134 SPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGI-----------LEIGDLMARYTSDVIG 187
            ||.||.:||:.||..:       |..|    |.|:..|           ||:.:|..|:.:|::.
Mosquito   144 SPAFTGSKMRLMFGLI-------TSYC----DGAVRTIRSELGADGTAELEMKELFRRFGNDIVA 197

  Fly   188 RCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGF----IESFPEVARFLRMRQIHQDITDF 248
            .||||:|.|..|:....|..:|:    |..:...|.|.    ..|||.|.|.||:|.....:|.|
Mosquito   198 TCAFGIEINSFRDRANAFFTLGK----ELTNLDGVQGLKFLAFSSFPRVMRALRLRLFSAKMTSF 258

  Fly   249 YVGIVRETVKQREEQGIVRSDFMNLLIE---------------------MKQRGELTIEEMAAQA 292
            :..:|.:|:.|||::||||.|.:|||::                     .|:..:.|.:::.||.
Mosquito   259 FRHVVMDTITQREQRGIVRHDMINLLMQARKQELRFDENENIETNGGGSQKRSVDWTDDDLTAQC 323

  Fly   293 FIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNG---EFTYDSMQELRYMELVI 354
            .:||..|:||.::...|..:|||..|.:|.:||:|||: :|...|   :..|:::|.:||:::|.
Mosquito   324 TVFFFGGYDTVSTLSAFMAHELAVNPDVQERLRDEIDR-VRSTIGSADKLNYETLQSMRYLDMVA 387

  Fly   355 AETLRKYPILPQLTRISRHLYAAK--GDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFL 417
            .|||||:...|.|.|.....|..:  ..|...::||..|.||...|..||.|:|||.:|.||||.
Mosquito   388 NETLRKWTPAPFLDRTCTKPYMLEDYDGRRVQLQPGDGLWIPAAAIMRDPQLFPEPDRFWPERFE 452

  Fly   418 ADQL-AQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILL 481
            .:.. |...::|.|.||.|||||||.||..|:|......||.:|.....|||...|...||::..
Mosquito   453 PESAGAPVDSSAMLAFGLGPRNCIGSRFALMETKAVFFFLLTHFLLEAGPRTQHPIRLKKSSLGP 517

  Fly   482 CPANGIYLK 490
            |...|.:::
Mosquito   518 CAEKGSWIR 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	161/464 (35%)
LOC1277432	XP_316781.2	CYP6-like	76..524	CDD:410679	161/465 (35%)