Protein Alignment Cyp6a22 and LOC1267986

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_001238280.1
• Gene: LOC1267986 / 1267986
• VectorBaseID: AGAMI1_005876
• Length: 541
• Species: Anopheles gambiae
• Alignment Length: 548
• Identity: 171/548 - (31%)
• Similarity: 276/548 - (50%)
• Gaps: 76/548 - (13%)

  Fly     2 LDVVALLLIA--LAVGFWFVRTRYSYWTRRGIGSEPARFPVGNMEGFR-KNKHFIDIVTPIYEKF 63
            ||:|.:..||  ||:.:::||.||.|:..:........|.:|:..... :.::.|..:..:|  :
Mosquito     3 LDMVTMAAIATILALLYYYVRNRYRYFLDKPYPHLKPTFLLGSSAPMMLRRRNMIQHIEALY--Y 65

  Fly    64 KGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMY-HNE-----RDDPLTGHLFRID 122
            ....|...|.:.:|.|.||:.|.:..|||.::||..|.|...: .||     .|:.....||.:.
Mosquito    66 SHPDAKVIGAYDLLTPNVLLRDPDCVKQIGVKDFDYFTDHTPFLPNESDIGQSDNMFLNSLFMLR 130

  Fly   123 GPKWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQ-VCGELADNAMCGILEIGDLMARYTSDVI 186
            |.|||.:|..:||.||.:||:.||..:.:..:.:.: :..|..::......|:.|:.:|:.:|||
Mosquito   131 GQKWRDMRATLSPAFTGSKMRQMFELMSDSCQGMVEHLLKEAREDESKQAHEMKDIFSRFANDVI 195

  Fly   187 GRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESF------------PEVARFLRMR 239
            ...|||:..|...:.|.:|...|:         ||:|  ..||            |.|...|.:.
Mosquito   196 ASIAFGIRVNSFADRENDFYTRGK---------KLLD--FSSFWPTIRFMLFMMVPRVMLKLDIE 249

  Fly   240 QIHQDITDFYVGIVRETVKQREEQGIVRSDFMNLLIEMKQRG----------------------- 281
            .:.:::...:..::.:.:|.|||:||||:|.:|:|:::| ||
Mosquito   250 LMDKEMCRHFHAMILDNMKVREEKGIVRNDMINILMQVK-RGALSHREDEPDVKDAGFATVHESA 313

  Fly   282 --------ELTIEEMAAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLRE---EIDQALRLH 335
                    |.|.:|:.||.|:||.|||||.::.|||.:|||.:...:|.:|.|   ||||  ||.
Mosquito   314 VGKKAITREWTEKELVAQCFLFFLAGFDTVSTALGFLMYELMRNREVQERLYEEIAEIDQ--RLD 376

  Fly   336 NGEFTYDSMQELRYMELVIAETLRKYPILPQLTRISRHLYA---AKGDRHFYIEPGQMLLIPVYG 397
            ....|||::|.:|||::|::|:||.:|..|.:.|.....|.   .:|.| |.||.|..:::||.|
Mosquito   377 GKPLTYDAVQGMRYMDMVVSESLRLWPPAPMVDRYCNRDYTFDDGEGLR-FKIEKGVTVMVPVAG 440

  Fly   398 IHHDPALYPEPHKFIPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHF 462
            :|.||..:|:|.:|.||||..:...:....|:||||.|||||||.||..|:....:..||::|.|
Mosquito   441 LHSDPKYFPDPKRFDPERFSEENRHKINPGAYLPFGVGPRNCIGSRFALMEVKSIIYYLLKSFTF 505

  Fly   463 SVCPRTDPKIEFLKSNILLCPANGIYLK 490
            ..|.:|...:....|.::|....||:::
Mosquito   506 ERCEQTQVPLRLKNSPVVLAAEKGIWIR 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	154/477 (32%)
LOC1267986	XP_001238280.1	CYP6-like	68..531	CDD:410679	154/477 (32%)