Protein Alignment Cyp6a22 and LOC11175638

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_003436913.2
• Gene: LOC11175638 / 11175638
• VectorBaseID: AGAMI1_004765
• Length: 509
• Species: Anopheles gambiae
• Alignment Length: 530
• Identity: 136/530 - (25%)
• Similarity: 242/530 - (45%)
• Gaps: 70/530 - (13%)

  Fly     4 VVALLLIALAVGFWFVRTRYSYWTRRGI--------GSEPARFPVGNMEGFRKNKHFIDIVTPIY 60
            |:.||:|.:..|...|     |..||.:        |::| .:.:||:..:..|.     :..|:
Mosquito     4 VLFLLVILIVYGLAQV-----YRKRRRLHRIAAHFDGAKP-HWLLGNVMEYPAND-----IPGIF 57

  Fly    61 EKF----KGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFRI 121
            |..    |.:|.....:.::...::.|:.....:::::   |...::...:...:..|...|...
Mosquito    58 ETMVALHKRHGKDLFNWGLLNDHMITVSSAANVEKVVM---AKRTEKSSVYEFIELWLGQGLLIS 119

  Fly   122 DGPKWRPLRQKMSPTFTSAKMKYMFPTVC-EVGEELTQVCGELADNAMCGILEIGDLMARYTSDV 185
            .|.||...|:.::||| ..|:...|.||. :..|.|.:...:.||...  ..:|.:.::.|..|.
Mosquito   120 KGEKWFHRRKIITPTF-HFKILESFVTVFNQEAEILIEKLSQYADTGR--EFDIYEPISLYALDS 181

  Fly   186 IGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESFPEVARFLR---------MRQI 241
            |...:.|||.|..|:||.:: :...:..||....::.. .:.|||....:..         :|::
Mosquito   182 ICTTSMGVEINAQRHPENQY-VRDVKRMSELILLRIFH-VLSSFPRTYWYTMPNAWEQRKLIRRL 244

  Fly   242 HQDITDFYVGIVRETVKQR-----------EEQGIV---RSDFMNLLIEMKQRG----ELTIEEM 288
            |. .||..:...||.:.:|           :|:.:.   |..|::||:.::..|    :|.|.|
Mosquito   245 HA-FTDTVIHKRREQLLERSSQVSNEQECLDEEHLYTKRRETFLDLLLNVRVDGNSLSDLDIRE- 307

  Fly   289 AAQAFIFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQAL--RLHNGEFTYDSMQELRYME 351
            ....|:|  .|.||:.|.:.|..|:|||.|.:|.||..||...|  ...:...||:::|...|::
Mosquito   308 EVDTFMF--EGHDTTTSGIAFTFYQLAKHPEIQEKLYREIQDVLGVEYRHVPLTYNTLQNFPYLD 370

  Fly   352 LVIAETLRKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERF 416
            :|:.|:||   :||.::.|.|.|..........|..|....||:|.||.:|.:||:|.:|.||||
Mosquito   371 MVVKESLR---LLPPVSFIGRRLADDIEMNGVTIPAGTDFTIPIYVIHRNPVVYPDPERFDPERF 432

  Fly   417 LADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILL 481
            ......:|....::||..|.|||||.|:..::..:.:|.:: :|:..:...|..:|. ||::::|
Mosquito   433 SDGNTQRRGPYDYIPFSIGSRNCIGQRYALLEMKVAIVRMV-SFYRILPGDTMHEIR-LKTDLVL 495

  Fly   482 CPANGIYLKV 491
            .|...|.:|:
Mosquito   496 RPDKSIPIKL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	117/451 (26%)
LOC11175638	XP_003436913.2	None