Protein Alignment Cyp6a22 and cyp46a1.4

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_002933245.2
• Gene: cyp46a1.4 / 100498621
• XenbaseID: XB-GENE-29072485
• Length: 504
• Species: Xenopus tropicalis
• Alignment Length: 531
• Identity: 136/531 - (25%)
• Similarity: 223/531 - (41%)
• Gaps: 103/531 - (19%)

  Fly     7 LLLIALAVGF--WFVRTRYSYWTRRGIGSEPA-RFPVGNMEGFRKNK-----------HFIDIVT 57
            |::|...|.|  :....:|.:.....|...|. .|.:|::....|.:           |:.:|..
 Frog    19 LIIIGAVVAFLAYCAYIKYMHLKYDDIPGPPRDSFLLGHIPTLSKAEENYSVVHDLFLHWAEIYG 83

  Fly    58 PIYEKFKGNGAPFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLT-GHLFRI 121
            |:   ||.|        ::.|.::..|..|..|:.|           |......||.| ..||.:
 Frog    84 PV---FKIN--------ILHRVMIYSTSPESVKECL-----------MSSKYPKDPYTYNQLFNL 126

  Fly   122 DGPK--------------WRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGIL 172
            .|.:              |...|:.|.|.|::..:|.|.....|..|::.:...|.||    |..
 Frog   127 FGKRFLGKGLLTDPDHDHWYHQRRIMDPAFSNTYLKEMIGIFNERAEQMMEKLEEKAD----GHQ 187

  Fly   173 EIG--DLMARYTSDVIGRCAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDG--------FIE 227
            |:.  .::.|.|.|||.:.|||::...:...:.:|.    .|.|     |::.|        :::
 Frog   188 EVSMHSIINRVTLDVITKVAFGMDLGLVEGNKTDFP----NAIS-----KVLTGMMRYMQNPYMQ 243

  Fly   228 SFPEVARFLRMRQIHQDITDFYVGIVRETVKQR-------EEQGIVRSDFMNLLIEMKQRGELTI 285
            .||:...|  :|:: |:..|......:|.:.||       ||   :..|.:..:::..:......
 Frog   244 YFPKHWAF--VREV-QESADLLRKTGKECISQRKKAMQNGEE---LPKDILTKILQCAELENALD 302

  Fly   286 EEMAAQAFI-FFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRY 349
            :|:....|| ||.||.:|:|:.|.|.:.||.:||.:..|||.|:|:.:.... :.:||.:|.|.|
 Frog   303 DEIMLDNFITFFIAGQETTANQLSFTVMELTRQPEIMTKLRMEVDEVIGFKR-DISYDDIQNLNY 366

  Fly   350 MELVIAETLRKYPILPQLTRISRHLYAAKGDRHF---YIEPGQMLLIPVYGIHHDPALYPEPHKF 411
            |..|:.|:||.||..|   ..||:|   |.|..|   .|..|..:....|.:......:.:|.||
 Frog   367 MTQVLKESLRFYPPGP---GTSRYL---KEDTIFEGIKIPGGVSITFNTYVMGRMEKFFQDPCKF 425

  Fly   412 IPERFLADQLAQRPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLK 476
            .||||  ...|.:|...:.||..|||:|:|..|.:::..:.|..|::.|.|.:.|.....|   |
 Frog   426 DPERF--HPAAVKPYFCYFPFALGPRSCLGQIFSQLEAKVILSKLIQRFEFELVPGQSFGI---K 485

  Fly   477 SNILLCPANGI 487
            ....|.|.:|:
 Frog   486 DTGTLRPRDGV 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	121/458 (26%)
cyp46a1.4	XP_002933245.2	CYP46A1-like	72..498	CDD:410706	126/478 (26%)