Protein Alignment Cyp6a22 and LOC100487054

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_002937893.2
• Gene: LOC100487054 / 100487054
• XenbaseID: XB-GENE-29078603
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 523
• Identity: 152/523 - (29%)
• Similarity: 245/523 - (46%)
• Gaps: 74/523 - (14%)

  Fly     7 LLLIALAVGFWFVRTRYSYWTRRGI-GSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKGNGAPF 70
            ||::.|.:..::....|..:.|.|| |..|..| :|...|.||.....|:     |.||..|..:
 Frog    14 LLVLLLTLLAYYAIWPYRLFKRYGIPGPTPIPF-IGTFLGNRKGLMEFDM-----ECFKKYGKVW 72

  Fly    71 AGFFMMLRPVVLVTDLELAKQILIQD-FANFEDRGMYHNERDDPLTGHL----FRIDGPKWRPLR 130
             |.:...:|::.:.|..:.|.|:|:: ::||.      |.||..|||.|    ......:|:.:|
 Frog    73 -GIYEGQKPLLAIVDPVIIKSIMIKECYSNFT------NRRDLGLTGPLKSSVLVSKDEQWKRIR 130

  Fly   131 QKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDVIGRCAFGVEC 195
            ..:||||||.|:|.|||.:...||.|.:...:..||.  ..|::..:...|:.|::...:|.|..
 Frog   131 TVLSPTFTSGKLKQMFPLMKHYGELLVKNIHKKIDNK--EPLDMKHIFGSYSMDIVLSTSFSVNV 193

  Fly   196 NGLRNPEAEFAIMGRRAF----------------------SERRHC----KLVDGFIESFPEVAR 234
            :.:.||...|....|..|                      .:...|    |:::.|.::...:.:
 Frog   194 DSMNNPNDPFVTNARNLFKFSFFNPLFLIAILCPFLVPLLDKMNFCFLSLKILNFFKDAVASIKK 258

  Fly   235 FLRMRQIHQDITDFYVGIV------RETVKQREEQGIVRSDFMNLLIEMKQRGELTIEEMAAQAF 293
             .|.:..|:|..|....:|      .|:|.:.|:.|.               .||:..|:.||:.
 Frog   259 -KRQKGTHEDRVDLLQLMVDAQSNEGESVPEEEKHGY---------------KELSDTEILAQSL 307

  Fly   294 IFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETL 358
            ||..||::|:::||.|..|.:|..|.:|.||.|||| ||..:....|||::.::.||::||.|||
 Frog   308 IFIMAGYETTSTTLMFLAYNIATHPDVQRKLEEEID-ALLPNKAPPTYDALMKMEYMDMVINETL 371

  Fly   359 RKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQ 423
            |.:|...::.|:.:......|   ..|..|.::::|::.:|.:|.::|||.:|.||||..:....
 Frog   372 RMFPPAIRIDRVCKKTMEING---VTIPAGVVIVVPLFVLHLNPEIWPEPEEFQPERFSKENQKN 433

  Fly   424 RPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPANGIY 488
            :....:||||.||||||||||..:...:.|..||:||.|..|..|...::......|. |...|.
 Frog   434 QDPYNFLPFGVGPRNCIGMRFALVNMKLVLTILLQNFRFETCKDTPVPLKICTDGYLK-PTKPII 497

  Fly   489 LKV 491
            |.:
 Frog   498 LNL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	132/458 (29%)
LOC100487054	XP_002937893.2	cytochrome_P450	67..498	CDD:477761	133/460 (29%)