Protein Alignment Cyp6a22 and Cyp4a32

DIOPT Version :10

• Sequence 1: NP_652075.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 526
• Identity: 133/526 - (25%)
• Similarity: 237/526 - (45%)
• Gaps: 83/526 - (15%)

  Fly     7 LLLIALAVGFWFVRTRYSYWTRRGI---GSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKGNGA 68
            |||:..||.|:..|.    |..:.:   .|.|..:..|: |.|:..:...::|:.| |.|.   :
Mouse    28 LLLLVKAVQFYLHRK----WLLKALQQFPSPPFHWFFGH-EQFKGEQELKEVVSCI-EHFP---S 83

  Fly    69 PFAGFFMMLRPVVLVTDLELAKQILIQDFANFEDRGMYHNERDDPLTGHLFR------------I 121
            .|..:|......:.|.|.:..|.||               .|.||....::|            :
Mouse    84 AFPCWFWGSNAYLTVYDPDYMKVIL---------------GRSDPKANGIYRLLAPWIGYGLLLL 133

  Fly   122 DGPKWRPLRQKMSPTF----TSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYT 182
            :|..|...|:.::|.|    ....:|.|..::..:.::..::.|:  |::    :||...::..|
Mouse   134 NGQPWFQHRRMLTPAFHYDILKPYVKNMADSIRLMLDKWERLAGQ--DSS----IEIFQHISLMT 192

  Fly   183 SDVIGRCAF----GVECNGLRNPEAEFAIMG--RRAFSER-RHCKLVDGFIESFPEVARFLRMR- 239
            .|.:.:|||    .|:.:|  |.:.....:|  ...|..| |:....:..|.......|..:..
Mouse   193 LDTVMKCAFSHKGSVQVDG--NYKTYLQAIGDLNNLFHSRVRNIFHQNDTIYRLSSNGRLAKQAC 255

  Fly   240 QIHQDITDFYVGIVRETVKQREEQGIV-------RSDFMNLLI--EMKQRGELTIEEMAAQAFIF 295
            |:..|.||   |:::....|.:::|.:       |.||:::|:  .|:....::.:::.|:...|
Mouse   256 QLAHDHTD---GVIKMRKDQLQDEGELENIKKKRRLDFLDILLFARMENGDSMSDKDLRAEVDTF 317

  Fly   296 FAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETLRK 360
            ...|.||:||.:.:..|.||..|..|.:.|||: |:|.......|:|.:.::.|..:.|.|.||.
Mouse   318 MFEGHDTTASGVSWIFYALATHPEHQQRCREEV-QSLLGDGSSITWDHLDQIPYTTMCIKEALRL 381

  Fly   361 YPILPQLTR-ISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQR 424
            ||.:|.:.| :|..:....|..   :..|..:.:.:||:||:|.::|.|..|.|.||..|  :.|
Mouse   382 YPPVPGIVRELSTSVTFPDGRS---LPKGVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPD--SPR 441

  Fly   425 PTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDP-KIEFLKSNILLCPANGIY 488
            .:.::|||..|.|||||.:|.  .:.:.::..|...||.:.|  || ::....:.|:|...||||
Mouse   442 HSHSFLPFSGGARNCIGKQFA--MSELKVIVALTLLHFELLP--DPTRVPEPLARIVLKSKNGIY 502

  Fly   489 LKVQQL 494
            |.:::|
Mouse   503 LHLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_652075.1	CYP6-like	66..488	CDD:410679	112/456 (25%)
Cyp4a32	NP_001093651.1	CYP4B-like	71..504	CDD:410771	118/472 (25%)