Protein Alignment Cyp6a22 and cyp3a5

DIOPT Version :9

• Sequence 1: NP_001286431.1
• Gene: Cyp6a22 / 49847
• FlyBaseID: FBgn0013773
• Length: 499
• Species: Drosophila melanogaster
• Sequence 2: XP_012819594.1
• Gene: cyp3a5 / 100037874
• XenbaseID: XB-GENE-5821575
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 523
• Identity: 151/523 - (28%)
• Similarity: 252/523 - (48%)
• Gaps: 74/523 - (14%)

  Fly     7 LLLIALAVGFWFVRTRYSYWTRRGI-GSEPARFPVGNMEGFRKNKHFIDIVTPIYEKFKGNGAPF 70
            ||::.|.:..::....|..:.|.|| |..|..| :|...|.|......|:     |.||..|..:
 Frog    14 LLVLLLTLLAYYAIWPYKLFKRYGIPGPTPIPF-IGTFLGNRHGLMEFDM-----ECFKKYGKVW 72

  Fly    71 AGFFMMLRPVVLVTDLELAKQILIQD-FANFEDRGMYHNERDDPLTGHLFRIDGP---------- 124
             |.:...:|::.:.|..:.|.|:::: :.||.      |.||       |.:.||
 Frog    73 -GIYEGQKPLLAIVDPVIIKSIMVKECYTNFT------NRRD-------FGLSGPLKSSVLISKD 123

  Fly   125 -KWRPLRQKMSPTFTSAKMKYMFPTVCEVGEELTQVCGELADNAMCGILEIGDLMARYTSDVIGR 188
             :|:.:|..:||||||.|:|.|||.:...||.|.:...:..:|.  ..|::..:...|:.|::..
 Frog   124 EQWKRIRTVLSPTFTSGKLKQMFPLMNHYGELLVKNIHKKINNK--EPLDMKHIFGSYSMDIVLS 186

  Fly   189 CAFGVECNGLRNPEAEFAIMGRRAFSERRHCKLVDGFIESF------PEVAR----FLRMRQIHQ 243
            .:|.|..:.:.||...|....|..|:......|   |:.|.      |.:.:    ||.::
 Frog   187 TSFSVNVDSMNNPNDPFVTNARNLFTFSFFNPL---FLISILCPFLVPLLDKMNFCFLSLK---- 244

  Fly   244 DITDFYVGIVRETVKQREEQGI--VRSDFMNLLI-----------EMKQRG--ELTIEEMAAQAF 293
             |.:|:...| .::|::.::|.  .|.||:.|::           |.::.|  ||:..|:.||:.
 Frog   245 -ILNFFKDAV-ASIKKKRQKGTHEDRVDFLQLMVDAQSNEGKSVPEEEKHGYKELSDTEILAQSL 307

  Fly   294 IFFAAGFDTSASTLGFALYELAKQPALQAKLREEIDQALRLHNGEFTYDSMQELRYMELVIAETL 358
            ||..||::|:::||.|..|.:|..|.:|.||.|||| ||..:....|||::.::.||::||.|:|
 Frog   308 IFIMAGYETTSTTLMFLAYNIATHPDVQRKLEEEID-ALLPNKAPPTYDALMKMEYMDMVINESL 371

  Fly   359 RKYPILPQLTRISRHLYAAKGDRHFYIEPGQMLLIPVYGIHHDPALYPEPHKFIPERFLADQLAQ 423
            |.:|...::.|:.:......|   ..|..|.::::|::.:|.:|.::|||.:|.||||..:....
 Frog   372 RMFPPAIRIDRVCKKTMEING---VTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERFSKENQKN 433

  Fly   424 RPTAAWLPFGDGPRNCIGMRFGKMQTTIGLVSLLRNFHFSVCPRTDPKIEFLKSNILLCPANGIY 488
            :....:||||.||||||||||..:...:.|..||:||....|..|...::......|. |...|.
 Frog   434 QDPYNFLPFGVGPRNCIGMRFALVNMKVALTILLQNFRLETCKDTPVPLKICTKGYLK-PTKPII 497

  Fly   489 LKV 491
            |.:
 Frog   498 LNL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a22	NP_001286431.1	p450	35..491	CDD:278495	143/492 (29%)
cyp3a5	XP_012819594.1	p450	39..500	CDD:278495	144/496 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010