Protein Alignment CycK and CCNL2

DIOPT Version :10

• Sequence 1: NP_788082.1
• Gene: CycK / 49816
• FlyBaseID: FBgn0025674
• Length: 400
• Species: Drosophila melanogaster
• Sequence 2: XP_011540518.1
• Gene: CCNL2 / 81669
• HGNCID: 20570
• Length: 553
• Species: Homo sapiens
• Alignment Length: 492
• Identity: 113/492 - (22%)
• Similarity: 172/492 - (34%)
• Gaps: 157/492 - (31%)

  Fly     3 CWYYDKKELRETPSILDGISFETERRYRKEGARFIMECGTKMGLGHNTMATGVVYFHRFYMFHSF 67
            |...|.| ||.|||:..|:..:||...|..|...|...|..:.|....||||.|.|.||:...||
Human    52 CLLPDDK-LRFTPSMSSGLDTDTETDLRVVGCELIQAAGILLRLPQVAMATGQVLFQRFFYTKSF 115

  Fly    68 -----------RSFPR----YVTACC------------------------------CLFFAGKVE 87
                       |...|    ...|||                              |:......|
Human   116 VKHSMEPSSLWRPSGRRGWGQTWACCNASASACVNGLCPPGFQDRRGPKTHTGRHQCVSPPSTAE 180

  Fly    88 ETPKKCRDIIKTARGILTDNYFYSFGDDPKEEVMTLERILLQTIKFDLQVEHPYTFLLKYAKCFK 152
            .....|....:....:|.|..:.:.    |.:::..||.:|:.:.|.:.|:||:..::.|.:..:
Human   181 RQKTLCSLSGRKPVPLLLDQDYVNL----KNQIIKAERRVLKELGFCVHVKHPHKIIVMYLQVLE 241

  Fly   153 GDQQKLQKMVQMAWNFVNDSLSTVVCLQWEPEIIAVALIHLASKLSKFTVQDWEGRQPQQQRWWD 217
            .::.  |.:||.:||::||||.|.|.::::||.||.|.|:||::..:..:       |.:..|:.
Human   242 CERN--QHLVQTSWNYMNDSLRTDVFVRFQPESIACACIYLAARTLEIPL-------PNRPHWFL 297

  Fly   218 MFVSDVTMEILEDICHQVLDLY-----------------------QSTQKEALQP--------TS 251
            :|  ..|.|.:::||.::|.||                       ...|...|.|        ||
Human   298 LF--GATEEEIQEICLKILQLYARKKVDLTHLEGEVEKRKHAIEEAKAQARGLLPGGTQVLDGTS 360

  Fly   252 PPQKPPSRADSPKSGKLTNSTGIGPLSVPQQPPPPVCGNGGVLEVSN----IQSIKSLASGVPII 312
            .....|...:|||.||            ..:|.|        |.|.|    ::..|...:..|:.
Human   361 GFSPAPKLVESPKEGK------------GSKPSP--------LSVKNTKRRLEGAKKAKADSPVN 405

  Fly   313 G-----------PSDSQNLLQGPTPPGQP------SGYHIYHAPPPPPPPVVPMPPYPSSGWGVQ 360
            |           .|..|:..:.|:....|      ||                    .:||....
Human   406 GLPKGRESRSRSRSREQSYSRSPSRSASPKRRKSDSG--------------------STSGGSKS 450

  Fly   361 QTVVGHYSGSAAPPPPMPPSLPPGASGYYNAGGRPSQ 397
            |:  ...|.|.:||...|.|.|  ..|....|.|.|:
Human   451 QS--RSRSRSDSPPRQAPRSAP--YKGSEIRGSRKSK 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CycK	NP_788082.1	CYCLIN_CCNK_rpt1	20..134	CDD:410233	32/158 (20%)
		CYCLIN_CCNK_rpt2	138..239	CDD:410234	30/100 (30%)
CCNL2	XP_011540518.1	CYCLIN_SF	35..223	CDD:477360	40/175 (23%)
		CYCLIN_CCNL2_rpt2	228..350	CDD:410296	34/132 (26%)