DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht4 and Chi3l1

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_001296749.1	Gene:	Chi3l1 / 89824	RGDID:	620874	Length:	391	Species:	Rattus norvegicus

Alignment Length:	401	Identity:	153/401 - (38%)
Similarity:	222/401 - (55%)	Gaps:	58/401 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 VSIWALAALCLCLGQVASSEKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHISYTFFGISDAGE 68
            |::...|.|.|.  |..|:.||: ||:..|:.||.|:|...|..:|.||||||.|:|..||:
  Rat    13 VALTGFAVLMLL--QSCSAYKLV-CYYTNWSQYREGNGSCFPDALDHSLCTHIIYSFANISN--- 71

  Fly    69 FKSLDT--WLDMDDGLGFISQTIALKQRNPNLKILAVVGGWNEGSTKYSAMAADPAKRATFVSTS 131
             ..|.|  |.|:.    .......||.|||.||.|..||||:.||.::|.:.::...|.|||.:.
  Rat    72 -NKLSTSEWNDVT----LYGMLNTLKTRNPRLKTLLSVGGWSFGSERFSRIVSNAKSRKTFVQSV 131

  Fly   132 LAFIQQYSFDGLDLDWEYPGQRGGSEADRENFVTLLREIKETYD---QYGLE---LGIAVGASEK 190
            ..|::.|.||||||.|.|||.:     |:::|.||::|:|..:.   |.|.|   |..||.|.:.
  Rat   132 APFLRTYGFDGLDLAWLYPGPK-----DKQHFTTLIKELKAEFTKEVQPGTEKLLLSAAVSAGKV 191

  Fly   191 SASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPL--------PEVAESIDYWLSH----G 243
            :....||:..|:|||.|||:||||||.......|.::||        |:...::||.:.:    |
  Rat   192 TLDSGYDVAQIAQHLDFINLMTYDFHGTWRHTTGHHSPLFRGQQDTGPDRFSNVDYGVGYMLRLG 256

  Fly   244 APAEKLILGIGFYGHSYQMSDSSQNWPGAACIGPGTAGVYTRENGFLGYHEICLNNWQTVFDQEN 308
            ||..||::||..:|.|:.:: ||:|..||...|.|..|.||:|.|.|.|:|||        |...
  Rat   257 APTNKLVMGIPTFGKSFTLA-SSENQVGAPITGSGLPGRYTKEKGTLAYYEIC--------DFLR 312

  Fly   309 GA----------PYAFQGDQWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRG-LCGES-- 360
            ||          |:|.:|:||:|||:|||::.|::.::::.|.|||:|:::.||||| .||.:
  Rat   313 GAEVHRILGQQVPFATKGNQWVGYDDPESVKNKVKYLKNKQLAGAMVWAVDLDDFRGSFCGHNVH 377

  Fly   361 YPLLKTMNRAL 371
            :||...:..||
  Rat   378 FPLTNAIKEAL 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	143/377 (38%)
		Glyco_18	28..351	CDD:214753	134/352 (38%)
		CBM_14	421..462	CDD:279884
Chi3l1	NP_001296749.1	Glyco_18	31..365	CDD:214753	136/356 (38%)
Chi3l1	NP_001296749.1	GH18_chitolectin_chitotriosidase	32..388	CDD:119351	144/378 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350376
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	338	1.000	Inparanoid score	I2302
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.910