DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht4 and Ctbs

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_112285.1	Gene:	Ctbs / 81652	RGDID:	621338	Length:	367	Species:	Rattus norvegicus

Alignment Length:	358	Identity:	80/358 - (22%)
Similarity:	132/358 - (36%)	Gaps:	94/358 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 DPSLCT----HISYTFFGISDAGEFKSLDTWLDMDDGLGFISQTIALKQRNPNLKILAVVGGWNE 109
            :.|||.    |..:..| :.|.|:    .||...|     .||          :..:||.|.::.
  Rat    30 EASLCRPIRHHRDFEVF-VFDVGQ----KTWKSYD-----WSQ----------ITTVAVFGKYDS 74

  Fly   110 GSTKYS-------AMAAD--------PAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQRGGSEAD 159
            ....|:       .:..|        |..||::::..:|..:....||:::|.|.  :...|..:
  Rat    75 ELMCYAHSKGARVVLKGDVALKDIINPTFRASWIAQKVALAKAQHMDGINIDIEQ--EVDCSSPE 137

  Fly   160 RENFVTLLREIKETYDQ--YGLELGIAVGASEKSA-SISYDIPAISQHLTFINVMTYDFHMAL-- 219
            .|....|:||..|.:.:  .|.::...|..|.|.. ...|:...|:....|:.||:||....:
  Rat   138 YEALTALVRETTEGFHREIEGSQVTFDVAWSPKGIDKRCYNYTGIADACDFLFVMSYDEQSQIWS 202

  Fly   220 DGYLGLNAPLPEVAESIDYWLSHGAPAEKLILGIGFYGHSYQMSDSSQN---------WPGAACI 275
            :.....|||..:.......:|..|....||::||.:||:.|...:.|::         :.||.|
  Rat   203 ECIAAANAPYNQTLTGYGDYLRMGISPRKLVMGIPWYGYDYICLNLSKDDVCAIAKVPFRGAPC- 266

  Fly   276 GPGTAGVYTRENGFLGYHEICLNNWQTVFDQENGAPYAFQGDQW--------------------I 320
             ...||           |::   .::.:..|.|.   :..|.||                    :
  Rat   267 -SDAAG-----------HQV---PYRVIMKQVNS---SVSGSQWNQDQQAPYYNYKDPTGRLHQV 313

  Fly   321 GYDNPESIQLKMQLVESRNLGGAMMWSIETDDF 353
            .||||.||.||...|:...|.|..||:....|:
  Rat   314 WYDNPRSISLKAAFVKHYGLRGIGMWNANCLDY 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	80/358 (22%)
		Glyco_18	28..351	CDD:214753	79/354 (22%)
		CBM_14	421..462	CDD:279884
Ctbs	NP_112285.1	GH18_chitobiase	23..363	CDD:119354	80/358 (22%)
Ctbs	NP_112285.1	Glyco_18	<100..343	CDD:214753	62/263 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D826687at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820