DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht4 and ctbs

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_001018565.1	Gene:	ctbs / 553763	ZFINID:	ZDB-GENE-050522-422	Length:	361	Species:	Danio rerio

Alignment Length:	363	Identity:	82/363 - (22%)
Similarity:	140/363 - (38%)	Gaps:	76/363 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 WANYRPGDGKFTPSDIDPSLCTHIS----YTFFGISDAGE--FKSLDTWLDMDDGLGFISQTIAL 91
            |:...|.:.|        .||..||    :..| :.|.||  :|..| |..       ::...|.
Zfish    17 WSKVCPCERK--------ELCQPISSQPAFEVF-VFDVGEKAWKFYD-WTK-------VTTIAAF 64

  Fly    92 KQRNPNLKILAVVGGWN---EGSTKYSAMAADPAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQR 153
            .|.:..|...|...|..   :|..:...: .||..|..::..::...:....||:::|.|...:.
Zfish    65 GQYDAELMCYAHSKGVRLVLKGDIRLPEI-VDPVNRTAWIQGNVKLAKSQFMDGINIDIEQAVET 128

  Fly   154 GGSEADRENFVTLLREIKETYDQYGLELGIAVGASEKSASIS----------YDIPAISQHLTFI 208
            |..|     :..|...:|||.:.:..|    :..|:.|..::          ||...|:.....:
Zfish   129 GSPE-----YYALTDLVKETTESFHTE----IPGSQVSFDVAWSPKCIDKRCYDYITIADSCDLL 184

  Fly   209 NVMTYDFHMAL--DGYLGLNAPLPEVAESIDYWLSHGAPAEKLILGIGFYGHSYQMSDSSQN--- 268
            .||:||....:  |.....|||..:...:.|.::|.....:||::|:.:||:.|...:.|::
Zfish   185 FVMSYDEQSQIWGDCIAMANAPYDQTLTAYDQYISMNIDPKKLVMGVPWYGYDYSCLNFSKDGVC 249

  Fly   269 ------WPGAACIGPGTAGVYTRENGFLGYHEICLNNWQT-----VFDQENGAPYAFQGD----- 317
                  :.||.|         :..:|....:.|.:....:     ::|:|..|||....|
Zfish   250 TIPKVPFRGAPC---------SDASGRQIPYSIMMKQINSSISGRLWDEEQRAPYYNYKDTEGMV 305

  Fly   318 QWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRG 355
            ..:.||:||||.||...|....|.|..||:....|:.|
Zfish   306 HQVWYDDPESIALKAAYVMQHGLKGIGMWNGNLLDYNG 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	82/363 (23%)
		Glyco_18	28..351	CDD:214753	80/357 (22%)
		CBM_14	421..462	CDD:279884
ctbs	NP_001018565.1	GH18_chitobiase	5..358	CDD:119354	82/363 (23%)
ctbs	NP_001018565.1	Glyco_18	<95..334	CDD:214753	58/256 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D826687at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920