DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht4 and chit1

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_001005792.1	Gene:	chit1 / 448265	XenbaseID:	XB-GENE-5801457	Length:	492	Species:	Xenopus tropicalis

Alignment Length:	491	Identity:	167/491 - (34%)
Similarity:	247/491 - (50%)	Gaps:	80/491 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 LNCYWGTWANYRPGDGKFTPSDIDPSLCTHISYTFFGISDAGEFKSLDTWLDMDDGLGFISQTIA 90
            |.||:..|:.|||...|:.|.:|||.||||:.|.|..::.    ..:..:...||.|  ..|..|
Frog    24 LVCYFTNWSQYRPEPAKYMPGNIDPKLCTHLIYAFATMNS----NKIAPYEWNDDVL--YKQYNA 82

  Fly    91 LKQRNPNLKILAVVGGWNEGSTKYSAMAADPAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQRGG 155
            |||:||||..|..:||||.|:.|::.|.:....|..|:.:.:.:::.|.|:|:|||:||||.||.
Frog    83 LKQQNPNLVTLLAIGGWNFGTQKFTEMVSSAGNRKIFIDSVIEYLRLYGFNGIDLDFEYPGSRGS 147

  Fly   156 SEADRENFVTLLREIKETYD-------QYGLELGIAVGASEKSASISYDIPAISQHLTFINVMTY 213
            ...|:..|..|.:|:.:.::       |..|.:..||.|.:.:....|:|..|.:.|.||:||||
Frog   148 PPEDKHRFTILTQEMLKAFEDEAAATNQSRLLMTAAVSAGKGTIDAGYEIAEIGKTLDFISVMTY 212

  Fly   214 DFHMALDGYLGLNAPLPE------------VAESIDYWLSHGAPAEKLILGIGFYGHSYQMSDSS 266
            |||...|...|.|:||.:            :..:::||..:|.||:||::|...||.:::..:.|
Frog   213 DFHGGWDPVSGHNSPLCKGSKDTGDFQYFNIRYAMNYWKDNGVPAQKLLIGFPTYGRTFRNPNPS 277

  Fly   267 QNWPGAACIGPGTAGVYTRENGFLGYHEIC------LNNWQTVFDQENGAPYAFQGDQWIGYDNP 325
            ....|....|.|:||.||||.||..|:|||      ..||  :.||:  .|||.:|::|:|:||.
Frog   278 NCDVGIPVSGAGSAGQYTREAGFWAYYEICTWLSGTTINW--IADQK--VPYACKGNEWVGFDNQ 338

  Fly   326 ESIQLKMQLVESRNLGGAMMWSIETDDFRG-LCGE-SYPLLKTMNRALGREVSGGSGGGGGGGGE 388
            :|.:.|::.::.....|||:|:|:.|||.| .|.: .|||:..:...|                |
Frog   339 DSYECKVKFLKESGFAGAMVWAIDLDDFSGTFCNQGKYPLISHLKSLL----------------E 387

  Fly   389 GSVTPAP----TAAPTSSPTPA-----------PTPG-----GGSGGNE-----CA--QDGFFVL 426
            ||||..|    ...||..|:|.           ||||     ..:.|:|     ||  .||.:..
Frog   388 GSVTKCPGNPCDIVPTEPPSPTTSGETTTSQAKPTPGETTTSTTTSGDEVDPNFCAGKSDGLYEN 452

  Fly   427 ESDCNKFYQCVGGVRYDFQCGAGLCFNTITLNCDWP 462
            ..:.|:||.|.||..|..:|..||.|:.....|:||
Frog   453 RINFNRFYICAGGSTYPMKCADGLVFDEACKCCNWP 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	132/371 (36%)
		Glyco_18	28..351	CDD:214753	123/347 (35%)
		CBM_14	421..462	CDD:279884	14/40 (35%)
chit1	NP_001005792.1	GH18_chitolectin_chitotriosidase	24..386	CDD:119351	132/371 (36%)
chit1	NP_001005792.1	CBM_14	442..491	CDD:366726	18/47 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	306	1.000	Inparanoid score	I2597
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.980