DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht4 and Cht9

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_611543.3	Gene:	Cht9 / 37392	FlyBaseID:	FBgn0034582	Length:	368	Species:	Drosophila melanogaster

Alignment Length:	370	Identity:	233/370 - (62%)
Similarity:	286/370 - (77%)	Gaps:	6/370 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KLVSIWALAALCLCLGQVASSEKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHISYTFFGISDA 66
            ||:::.|:    |||.||..:|:::|||||||||||.|:|||..|:||..||||:||:||||:|.
  Fly     3 KLLALLAV----LCLSQVIGAERIVNCYWGTWANYRSGNGKFDVSNIDAGLCTHLSYSFFGINDN 63

  Fly    67 GEFKSLDTWLDMDDGLGFISQTIALKQRNPNLKILAVVGGWNEGSTKYSAMAADPAKRATFVSTS 131
            ||.:|||||||.|  ||||:|.|:||.:|.|||:|||||||||||||||:|:.|..||..|::::
  Fly    64 GEIQSLDTWLDYD--LGFINQAISLKNQNSNLKVLAVVGGWNEGSTKYSSMSGDWYKRQNFINSA 126

  Fly   132 LAFIQQYSFDGLDLDWEYPGQRGGSEADRENFVTLLREIKETYDQYGLELGIAVGASEKSASISY 196
            |..::.:.|||||||||||.||||:..||.|||||||||||.:..||.||||||||.|..||.||
  Fly   127 LNLLRNHGFDGLDLDWEYPNQRGGNWNDRANFVTLLREIKEAFAPYGYELGIAVGAGESLASASY 191

  Fly   197 DIPAISQHLTFINVMTYDFHMALDGYLGLNAPLPEVAESIDYWLSHGAPAEKLILGIGFYGHSYQ 261
            :|..|:|.:.|||||||||.||.||..|.|||...|..:|::|||.||||.||:||:|.||.|:|
  Fly   192 EIANIAQQVDFINVMTYDFAMASDGQTGFNAPQWAVENAINFWLSQGAPANKLVLGVGTYGRSFQ 256

  Fly   262 MSDSSQNWPGAACIGPGTAGVYTRENGFLGYHEICLNNWQTVFDQENGAPYAFQGDQWIGYDNPE 326
            :||||||||||.|.|.|:||.||...|:|||:|||.|||.||||.:|.||||:.||||:.:||..
  Fly   257 LSDSSQNWPGAPCRGEGSAGSYTGSTGYLGYNEICQNNWHTVFDYDNAAPYAYSGDQWVSFDNVL 321

  Fly   327 SIQLKMQLVESRNLGGAMMWSIETDDFRGLCGESYPLLKTMNRAL 371
            |:|.||....|:.|.|||:||:||||:||.|||:||||||:||.|
  Fly   322 SVQYKMDFALSKGLAGAMIWSLETDDYRGQCGETYPLLKTINRKL 366

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	223/344 (65%)
		Glyco_18	28..351	CDD:214753	206/322 (64%)
		CBM_14	421..462	CDD:279884
Cht9	NP_611543.3	GH18_chitolectin_chitotriosidase	23..366	CDD:119351	223/344 (65%)
Cht9	NP_611543.3	Glyco_18	23..346	CDD:214753	207/324 (64%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469216
Domainoid	1	1.000	188	1.000	Domainoid score	I962
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	160	1.000	Inparanoid score	I1632
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		mtm1002
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	10	9.900