DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht4 and Idgf6

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_001286499.1	Gene:	Idgf6 / 36868	FlyBaseID:	FBgn0013763	Length:	452	Species:	Drosophila melanogaster

Alignment Length:	456	Identity:	132/456 - (28%)
Similarity:	208/456 - (45%)	Gaps:	98/456 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IWALAALCLCLGQVASS--------EKLLNCYWGTWANYRPGDGKFTPSDIDPSL--CTHISYTF 60
            |.|||.:.|||..:.:|        :|.|.||:.:.:..:.|.||....:::|:|  |.::.|.:
  Fly     3 IKALAIVSLCLASIQASKVGAPQLPKKHLVCYYDSASFVKEGLGKLVIDELEPALQFCDYLVYGY 67

  Fly    61 FGIS-DAGEFKSLDTWLDMDDGLGFISQTIALKQRNPNLKILAVVGG---------WNEGSTKYS 115
            .||. |:.:..||:..||:|.|.|.......||::.||:|||..|||         ..|...||.
  Fly    68 AGIERDSHKAVSLNQQLDLDLGKGLYRTVTRLKRKYPNVKILLSVGGDKDIELDKDAKELPNKYL 132

  Fly   116 AMAADPAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQR-------------------GG------ 155
            .:...|..|..||:|..:.::.|.|||||:.|::|..:                   .|
  Fly   133 ELLESPTGRTRFVNTVYSLVKTYGFDGLDVAWQFPKNKPKKVHSGIGSLWKGFKKVFSGDSIVDE 197

  Fly   156 -SEADRENFVTLLREIKETYDQYGLELGIAVGASEKSASISYDIPAISQHLTFINVMTYDF---- 215
             ||..:|.|..|||::|..:....|.|...| ....::|:.|||||:..:|.|:|:.|:||
  Fly   198 KSEEHKEQFTALLRDVKNAFRPDNLLLSTTV-LPNVNSSLFYDIPAVVNYLDFVNLGTFDFFTPQ 261

  Fly   216 -HMALDGYLGLNAPL-------PE--VAESIDYWLSHGAPAEKLILGIGFYGHSYQMSDSSQNWP 270
             :..:..|.   ||:       ||  ||..:.|||.:..||.|:.:|:..||..::::|.|
  Fly   262 RNPEVADYA---APIYELSERNPEFNVAAQVKYWLRNNCPASKINVGVATYGRPWKLTDDS---- 319

  Fly   271 GAACIGP-------GTAGVYTRENGFLGYHEIC--LNNWQTVFDQENGAP-------------YA 313
            |...:.|       ...|..|:..|...:.|:|  |.|....:.:...||             ||
  Fly   320 GDTGVPPVKDVKDEAPVGGNTQVPGIYSWPEVCALLPNQNNAYLKGANAPLIKVQDPAKRFGSYA 384

  Fly   314 F-----QGDQ--WIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRGLC-GESYPLLKTMNRA 370
            :     :||.  |:.:::|::...|...|.:.||||..::.:..||||||| .|.||:|:.:...
  Fly   385 YRAADKKGDNGIWVSFEDPDTAADKAGYVRTENLGGVALFDLSYDDFRGLCTNEKYPILRAIKYR 449

  Fly   371 L 371
            |
  Fly   450 L 450

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	122/426 (29%)
		Glyco_18	28..351	CDD:214753	110/403 (27%)
		CBM_14	421..462	CDD:279884
Idgf6	NP_001286499.1	GH18_IDGF	30..450	CDD:119352	122/427 (29%)
Idgf6	NP_001286499.1	Glyco_18	31..429	CDD:214753	111/405 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463799
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I1336
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	6	5.890