DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht4 and CG8460

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_609190.2	Gene:	CG8460 / 34115	FlyBaseID:	FBgn0031996	Length:	402	Species:	Drosophila melanogaster

Alignment Length:	246	Identity:	57/246 - (23%)
Similarity:	96/246 - (39%)	Gaps:	40/246 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 MAADPAKRATFVSTSLAFIQQYSFDGLDLD-WEYPGQRGGSEADRENFVTLLREIKETYDQYGLE 180
            :.:|..:|.......:...:...||||.|: |   .|..|...|:..:..:|:..||...|. |.
  Fly   172 LLSDAQERTKVNDVLIKCCKDNGFDGLVLEVW---SQLAGRIDDKILYTLVLQMAKELQKQQ-LR 232

  Fly   181 LGIAVGASEKSASISY---DIPAISQHLTFINVMTYDFHMALDGYLGLNAPLPEVAESIDYWLSH 242
            |.:.:....|.....:   .:..:.:|:...::|||||......  |.||||..|.::::.....
  Fly   233 LILVIPPFRKETGHLFGEKHMDKLFKHIYAFSLMTYDFSSVQRP--GANAPLYFVRKAVETIAPE 295

  Fly   243 G-----APAEKLILGIGFYGHSYQMSDSSQNWPGAACIGPGTAGVY----TRENGFLGYHEICLN 298
            |     |...|::||:..||:.|.....          ||.|...|    ......|.|.|..:.
  Fly   296 GCADMTAKRAKILLGLNMYGNDYTPDGG----------GPITFSQYLDLVRHVKKHLTYDERDVE 350

  Fly   299 NWQTVFDQENGAPYAFQGDQWIGYDNPESIQLKMQLVESRNLG-GAMMWSI 348
            |:   |:.:|.     .|...:.|....||..:::|  ::.|| |..:|.:
  Fly   351 NF---FEIKND-----DGRHIVFYPTLYSINERIKL--AQELGTGISIWEL 391

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	57/246 (23%)
		Glyco_18	28..351	CDD:214753	57/246 (23%)
		CBM_14	421..462	CDD:279884
CG8460	NP_609190.2	GH18_SI-CLP	81..402	CDD:119355	57/246 (23%)
CG8460	NP_609190.2	Glyco_18	86..393	CDD:214753	57/246 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463830
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930