DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht4 and Idgf4

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster

Alignment Length:	444	Identity:	126/444 - (28%)
Similarity:	209/444 - (47%)	Gaps:	75/444 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLVSIWALAALCLCLGQV--ASSEKLLNCYWGTWANYRPGDGKFTPSDIDPSL--CTHISYTFF 61
            |||.::::|....|.:||:  |.|..|| ||:...:..|.|..|...:|::|:|  |||:.|.:.
  Fly     1 MKLYALFSLLVGSLAIGQISAAGSHHLL-CYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYA 64

  Fly    62 GIS-DAGEFKSLDTWLDMDDGLGFISQTIALKQRNPNLKILAVVGGWNE----GSTKYSAMAADP 121
            ||: .:.:..|.:..||:|.|.....|...||::.|.||:|..|||..:    .:.||..:....
  Fly    65 GINPSSNKLVSNNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLESS 129

  Fly   122 AKRATFVSTSLAFIQQYSFDGLDLDWEYP--------GQRG------------------GSEADR 160
            ..|..|::::.:.::.|.||||||.|::|        |..|                  .:|..:
  Fly   130 NARIPFINSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHK 194

  Fly   161 ENFVTLLREIKETYDQYGLELGIAVGASEKSASISYDIPAISQHLTFINVMTYDFHM--ALDGYL 223
            |.|..|:||:|..:...|..||::| ....::|:.:|:|||..:|.::|:.||||..  ..:...
  Fly   195 EAFTALVRELKNAFRPDGYILGLSV-LPNVNSSLFFDVPAIINNLDYVNLHTYDFQTPERNNEVA 258

  Fly   224 GLNAPLPEVAE---------SIDYWLSHGAPAEKLILGIGFYGHSYQMS-DSSQNW--PGAACIG 276
            ...||:.|:.|         .:.||..:.|||.|:.:||..||.::::: ||....  |.|...|
  Fly   259 DFPAPIYELNERNPEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPVAEADG 323

  Fly   277 PGTAGVYTRENGFLGYHEICLNNWQTVFDQENGA---------------PYAFQ-----GDQ--W 319
            ...||..|:..|.|.:.|:|............||               .||::     |:.  |
  Fly   324 VAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGENGVW 388

  Fly   320 IGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRGLC--GESYPLLKTMNRAL 371
            :||::|::..:|.:.|:...|||..:..:..|||||.|  .:.:|:|:.:...|
  Fly   389 VGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL 442

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	115/415 (28%)
		Glyco_18	28..351	CDD:214753	106/391 (27%)
		CBM_14	421..462	CDD:279884
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	116/417 (28%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	108/394 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463798
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I1336
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	6	5.890