DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht4 and Chil5

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_001074285.1	Gene:	Chil5 / 229687	MGIID:	2676649	Length:	431	Species:	Mus musculus

Alignment Length:	446	Identity:	153/446 - (34%)
Similarity:	225/446 - (50%)	Gaps:	71/446 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 KLVSIWALAALCLCLGQVASSEKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHISYTFFG---- 62
            ||:.:..||   |.|.....|...|.||:...|..||..|.|.|:||||.||||:.|.|.|
Mouse     3 KLILVTGLA---LLLNPQLGSAYQLMCYYNNVAQNRPKLGSFNPADIDPCLCTHLIYAFAGMQNN 64

  Fly    63 ------ISDAGEFKSLDTWLDMDDGLGFISQTIALKQRNPNLKILAVVGGWNEGSTKYSAMAADP 121
                  ::|..::::|:|                ||.||..||.|..:||.:.|...:|||.:.|
Mouse    65 KVTMRSMNDLTDYQALNT----------------LKSRNVQLKTLLAIGGRDFGPAPFSAMVSTP 113

  Fly   122 AKRATFVSTSLAFIQQYSFDGLDLDWEYPGQRGGSEADRENFVTLLREIKETYDQYGLE------ 180
            ..:.||:::::.|::||.||||:|||::||.||....|:..|..|:::|:|.::...:|
Mouse   114 HNQQTFINSAIKFLRQYGFDGLNLDWQFPGSRGSPSRDKHLFTVLVQKIREAFELEAIENKSPRL 178

  Fly   181 -LGIAVGASEKSASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPLPE------------V 232
             :...|.....:....|:||.:|..|.:|.||||:.|.:.|||.|.|:||.:            |
Mouse   179 MVTATVAGVISTIQSGYEIPQLSHFLDYIQVMTYNLHGSQDGYTGENSPLYKSLNDTGINTLLNV 243

  Fly   233 AESIDYWLSHGAPAEKLILGIGFYGHSYQMSDSSQNWPGAACIGPGTAGVYTRENGFLGYHEIC- 296
            ...:.||..:||..||||:|...||.::.:||.|.|...|.....||.|.||.|:|...|:|||
Mouse   244 DYIMTYWNENGAAPEKLIVGFPAYGQTFTLSDPSNNGISAPTASAGTLGPYTEESGTWAYYEICS 308

  Fly   297 -LNNWQT-VFDQENGAPYAFQGDQWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRG-LCG 358
             ||:..| .:|.....|||:||::|:||||.:|.::|.:.::..||||||:|:::.|||.| .|.
Mouse   309 FLNDGATEAWDSAQEVPYAYQGNKWVGYDNVKSFRIKAEWLKQNNLGGAMLWTLDMDDFTGSFCN 373

  Fly   359 E-SYPLLKTMNRAL------------------GREVSGGSGGGGGGGGEGSVTPAP 395
            : .:||..|:..||                  ....||......|.....||:|.|
Mouse   374 QGQFPLTSTLKNALLVYSTSCMASVSDLQQVNAPLYSGNRNWKRGSKAMDSVSPVP 429

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	137/378 (36%)
		Glyco_18	28..351	CDD:214753	128/354 (36%)
		CBM_14	421..462	CDD:279884
Chil5	NP_001074285.1	GH18_chitolectin_chitotriosidase	24..387	CDD:119351	137/378 (36%)
Chil5	NP_001074285.1	Glyco_18	26..365	CDD:214753	128/354 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	339	1.000	Inparanoid score	I2351
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.080