DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht4 and chil-25

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_001300596.1	Gene:	chil-25 / 188614	WormBaseID:	WBGene00011846	Length:	483	Species:	Caenorhabditis elegans

Alignment Length:	408	Identity:	85/408 - (20%)
Similarity:	156/408 - (38%)	Gaps:	73/408 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MKLVSIWAL----------AALCLCLGQVASSEKLLNCYWGTWANY-RPGDGKFTPSDIDPSLCT 54
            |.|:.||.|          :.......::..:..:.||.......| |....|.|  .:..|..|
Worm    70 MLLLGIWFLIWSFDTVEKKSRTSTIQPKIDPTSTVSNCNKRVVGYYSRSETSKIT--SVQVSKLT 132

  Fly    55 HISYTFFGISDAGEFKSLDTWLDMDDGLGFISQTIALKQRNPNLKILAVVGGWNEGSTKYSAMAA 119
            |..:.|..::..|..|    :...|:...|:.....:......:||:..:|| .|.|..:|.:..
Worm   133 HAVFAFVYMNSDGTLK----FEKQDEEDRFMQLKDIVNMGTSPVKIMISIGG-KENSQNFSPVIE 192

  Fly   120 DPAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQRGGSEADRENFVTLLREIKETYDQYGLELGIA 184
            ...:|..|:::.|.|:::...||:||.||:|...  .::...:|:..|::..:|.|:..: |.|.
Worm   193 SEYRRQIFINSILTFLKENDLDGIDLFWEWPCST--YKSVYLHFICELKQQLQTKDKDYI-LSIV 254

  Fly   185 VGASEKSASI-SYDIPAISQHLTFINVMTYDFHMALDGYLG-LNAPLPEVAESI----DYWLSHG 243
            |...|....| .:|:..|.|.:.||||.:.|::.......| :..|...:...:    .:.:.|.
Worm   255 VPPPEVGGWIDGFDMNNIVQIVDFINVFSLDYYGPTQNDFGKITGPTAPMFNGVPGRETFNVDHT 319

  Fly   244 A--------PAEKLILGIGFYGHSYQMSDSSQNWPGAACIGP-GTAGVYTRENGFLGYHEICLNN 299
            :        .:.|..:.|.||         :..|....  || ....::...|...| ..:..::
Worm   320 SKVLSCETMQSNKFNIAIPFY---------TTLWENVQ--GPIDKIEIFRNVNKVHG-KIVGQSH 372

  Fly   300 WQTVFDQENG---APYAFQGDQ------------WIGYDNPESIQLKMQLVESRNLGGAMMWSIE 349
            ...:..|:.|   .||:|....            ::.::..:||..|::.|....|||..:|:::
Worm   373 MSRMIVQQKGFVLTPYSFDNATRNAFIYNSSTKIYLTFETDQSIVAKIEYVSEHLLGGICIWTVD 437

  Fly   350 TDD----------FRGLC 357
            .||          |.|||
Worm   438 KDDEGNSQLNAISFDGLC 455

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	80/373 (21%)
		Glyco_18	28..351	CDD:214753	73/353 (21%)
		CBM_14	421..462	CDD:279884
chil-25	NP_001300596.1	Glyco_18	110..439	CDD:214753	72/350 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164273
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D826687at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.750