DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht4 and chil-4

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_496125.1	Gene:	chil-4 / 182434	WormBaseID:	WBGene00007469	Length:	457	Species:	Caenorhabditis elegans

Alignment Length:	357	Identity:	75/357 - (21%)
Similarity:	146/357 - (40%)	Gaps:	84/357 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 LCTHISYTF---------FGISDAGEFKSLDTWLDMDDGLGFISQTIALKQRNPNLKILAVVGGW 107
            :.|||.|.|         ||    || :|...:.:|.:         ..::.|..||::..:||
Worm   131 MLTHIIYLFAIPKNGNMTFG----GE-RSRRKFEEMKN---------EARKANSTLKVMISIGG- 180

  Fly   108 NEGSTKYSAMAADPAKRATFVSTSLAFIQQYSFDGLDLDWEYPGQRGGSEADRENFVTLLREIKE 172
            ...|..:|.:.::...|..||::.::|:|:|..||:::.|.:|     ...|..|::..::|::.
Worm   181 QSNSRSFSRLVSNETSRNVFVNSIVSFVQKYDIDGIEIFWTWP-----KYEDANNYLIFIQELRY 240

  Fly   173 TYDQYGLEL--------GIAVGASEKSASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPL 229
            .:.:...:|        .|.|...:...|   ::...|:.:.|.|:  |..|.. ...:|.::||
Worm   241 AFIELQKKLNRKEDYVISIIVNCYDNQLS---NLMGFSKFVDFFNI--YSIHYQ-SRQVGPSSPL 299

  Fly   230 -----PEVAESIDYWLSHGAPAEKLILGIGFYGHSYQMSDSSQNWPGAAC-IGPGTAGVYTRENG 288
                 ..:.|::.|::.......|..:.:.|:|         ..|.||.. :...:..::..:|.
Worm   300 YGGGSRNIDETMKYYICRTGQPSKFNMMVLFHG---------TFWKGAELPLRNDSDDIFKDQNS 355

  Fly   289 FLG-----YHEICLNNW---QTVFDQENGAPYAFQGDQWI-------GYDNPESIQLKMQLVESR 338
            ..|     :.|:....|   ...|.......|     .||       ..::.:|:::|.:.|...
Worm   356 AKGGFAVRWRELLQQKWDMSNIKFHNLTKTSY-----MWIPGSSLFLTLEDEQSLRVKNRYVADH 415

  Fly   339 NLGGAMMWSIETDDFRGLCGESYPLLKTMNRA 370
            |:||..||:|:.||     |: :.|||.::.|
Worm   416 NIGGITMWTIDQDD-----GD-HTLLKVVSSA 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht4	NP_524962.2	GH18_chitolectin_chitotriosidase	26..371	CDD:119351	75/357 (21%)
		Glyco_18	28..351	CDD:214753	68/336 (20%)
		CBM_14	421..462	CDD:279884
chil-4	NP_496125.1	Glyco_18	111..428	CDD:214753	68/336 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164259
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG58170
OrthoDB	1	1.010	-	-		D826687at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.760