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Protein Alignment Cht4 and CHIT1

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_003456.1	Gene:	CHIT1 / 1118	HGNCID:	1936	Length:	466	Species:	Homo sapiens

Alignment Length:	495	Identity:	174/495 - (35%)
Similarity:	255/495 - (51%)	Gaps:	76/495 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 WA--LAALCLCLGQVASSEKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHISYTFFGISDAGEF 69
            ||  :..|.:..|..|.    |.||:..||.||.|:.:|.|.|:|||||||:.|.|.|:::
Human     7 WAGFMVLLMIPWGSAAK----LVCYFTNWAQYRQGEARFLPKDLDPSLCTHLIYAFAGMTN---- 63

  Fly    70 KSLDT--WLDMDDGLGFISQTI-----ALKQRNPNLKILAVVGGWNEGSTKYSAMAADPAKRATF 127
            ..|.|  |.|         :|:     .||:.||.||.|..:||||.|:.|::.|.|....|.||
Human    64 HQLSTTEWND---------ETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANNRQTF 119

  Fly   128 VSTSLAFIQQYSFDGLDLDWEYPGQRGGSEADRENFVTLLREIKETYDQYG-------LELGIAV 185
            |::::.|:::||||||||||||||.:|....|:|.|.||::::...:.|..       |.|..||
Human   120 VNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGKERLLLSAAV 184

  Fly   186 GASEKSASISYDIPAISQHLTFINVMTYDFHMALDGYLGLNAPLPE------------VAESIDY 238
            .|.:......|::..|:|:|.|:|:|.||||.:.:...|.|:||.:            |..::..
Human   185 PAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEKVTGHNSPLYKRQEESGAAASLNVDAAVQQ 249

  Fly   239 WLSHGAPAEKLILGIGFYGHSYQMSDSSQNWPGAACIGPGTAGVYTRENGFLGYHEICLNNW--- 300
            ||..|.||.|||||:..||.|:.::.||....||...|.||.|.:|:|.|.|.|:|:|  :|
Human   250 WLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGPFTKEGGMLAYYEVC--SWKGA 312

  Fly   301 --QTVFDQENGAPYAFQGDQWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRGL-CGES-Y 361
              |.:.||:  .||.|:.:||:|:|:.||.:.|:..::.:.|||||:|:::.|||.|. |.:. |
Human   313 TKQRIQDQK--VPYIFRDNQWVGFDDVESFKTKVSYLKQKGLGGAMVWALDLDDFAGFSCNQGRY 375

  Fly   362 PLLKTMNRALGREV--SGGSGGGGGGGGEGSVTP---APTAAPTSSPTPAPTPGGGSGGNECAQD 421
            ||::|:.:.|....  ||              ||   .|.....|.|...|:||..:.....| |
Human   376 PLIQTLRQELSLPYLPSG--------------TPELEVPKPGQPSEPEHGPSPGQDTFCQGKA-D 425

  Fly   422 GFFVLESDCNKFYQCVGGVRYDFQCGAGLCFNTITLNCDW 461
            |.:....:.:.||.|..|..:...|..||.|:.....|.|
Human   426 GLYPNPRERSSFYSCAAGRLFQQSCPTGLVFSNSCKCCTW 465

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.