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Protein Alignment Cht4 and CHI3L2

DIOPT Version :9

Sequence 1:	NP_524962.2	Gene:	Cht4 / 49815	FlyBaseID:	FBgn0022700	Length:	462	Species:	Drosophila melanogaster
Sequence 2:	NP_003991.2	Gene:	CHI3L2 / 1117	HGNCID:	1933	Length:	390	Species:	Homo sapiens

Alignment Length:	394	Identity:	141/394 - (35%)
Similarity:	223/394 - (56%)	Gaps:	41/394 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SIWALAALCLCLGQVASSEKLLNCYWGTWANYRPGDGKFTPSDIDPSLCTHISYTFFGISDAGEF 69
            |:|| ..:.|.|.|..|:.||: ||:..|:..|...|||||.:|||.||:|:.|:|..|.:
Human    10 SLWA-GVVVLLLLQGGSAYKLV-CYFTNWSQDRQEPGKFTPENIDPFLCSHLIYSFASIEN---- 68

  Fly    70 KSLDTWLDMDDGLGFISQTI-ALKQRNPNLKILAVVGGWNEGSTKYSAMAADPAKRATFVSTSLA 133
               :..:..|.....:.||| :||.:||.||||..:||:..||..:..|......|..|:::.:.
Human    69 ---NKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIIL 130

  Fly   134 FIQQYSFDGLDLDWEYPGQRGGSEADRENFVTLLREIKETYD-------QYGLELGIAVGASEKS 191
            |::.::|||||:.|.||.|:     :..:|..|:.|:.|.:.       :..|.|...|.|..:.
Human   131 FLRNHNFDGLDVSWIYPDQK-----ENTHFTVLIHELAEAFQKDFTKSTKERLLLTAGVSAGRQM 190

  Fly   192 ASISYDIPAISQHLTFINVMTYDFHMALDGYL--GLNAPLPE------------VAESIDYWLSH 242
            ...||.:..:::.|.|||::::|||.:.:..|  |.|:||.:            |..::.||:..
Human   191 IDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHK 255

  Fly   243 GAPAEKLILGIGFYGHSYQMSDSSQNWPGAACIGPGTAGVYTRENGFLGYHEIC--LNNWQTVFD 305
            |.|:||:::||..||||:.:: |::...||...|||.||..|..:|||.|:|||  |...:....
Human   256 GMPSEKVVMGIPTYGHSFTLA-SAETTVGAPASGPGAAGPITESSGFLAYYEICQFLKGAKITRL 319

  Fly   306 QENGAPYAFQGDQWIGYDNPESIQLKMQLVESRNLGGAMMWSIETDDFRG-LCGES-YPLLKTMN 368
            |:...|||.:|:||:|||:.:|::.|:|.:::.||||||:|||:.|||.| .|.:. |||::.:.
Human   320 QDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGPYPLVQAVK 384

  Fly   369 RALG 372
            |:||
Human   385 RSLG 388

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.