Protein Alignment eIF4H1 and eIF4H2

DIOPT Version :9

• Sequence 1: NP_001285330.1
• Gene: eIF4H1 / 49809
• FlyBaseID: FBgn0262734
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_001263122.1
• Gene: eIF4H2 / 43645
• FlyBaseID: FBgn0039797
• Length: 459
• Species: Drosophila melanogaster
• Alignment Length: 440
• Identity: 168/440 - (38%)
• Similarity: 213/440 - (48%)
• Gaps: 120/440 - (27%)

  Fly     4 RGGYEHARSGFGGDRASKQLPTEPPFIAFVGNLPQGLVQGDVIKIFQDFEVKYVRLVKDRETDQF 68
            |..:::.|:........:|:||||||||:|||||:|||||||:|||.|||||.|||:||||||:|
  Fly    38 RSNFQNYRNRDRDRDRQRQVPTEPPFIAYVGNLPKGLVQGDVMKIFSDFEVKNVRLIKDRETDEF 102

  Fly    69 KGFCYVEFETLDNLERALECDGRIKLDDLSAPLRIDIADRRKND-----------------RPGG 116
            ||:.|||||||..|:.||.|:||||||:.||||||||||.|:.:                 ..||
  Fly   103 KGYGYVEFETLAQLKSALNCNGRIKLDNFSAPLRIDIADHRRQNPGAPSGVGGAPPAGVGHERGG 167

  Fly   117 GVG-GGNGGMTRGDG--------------GRDGFQKRGP-------------PRQGGSSQSY--- 150
            ||| ||:.|...|:.              |...|::|.|             |.|..:|.:|
  Fly   168 GVGRGGSTGAANGNNPYYQRRNYRRDDSVGSHQFRRREPRSNSSNHQMSNSSPTQSTTSINYNRT 232

  Fly   151 SRGGPGT-----GGGGREGGGGSGNRGDSRGSYIDSYGGHN-----------DRSRGVGGSGAGS 199
            :|||..:     |.|.|..||...|..|.........||..           :.|.|.||:|.|.
  Fly   233 TRGGFNSRVAVGGNGNRYQGGAPRNFNDREDQQSTGSGGFQRNRTYNFNRSMNNSVGGGGAGVGR 297

  Fly   200 GGGMNRGYNDRPANRGRYGSFNNDDRPFERNQDRDRGQREGSYGNQSRDGDRYNNF--NRHRDRE 262
            ||...|.:|.. ...|.:|..|.                          |..|.||  ||:|||
  Fly   298 GGHPQRNFNGN-GGGGGFGVVNG--------------------------GGNYTNFVQNRNRDR- 334

  Fly   263 RTHYNPNQQSERPSGGMTGLGGGSGGSGGLGVGGGSSMGAIDNFRHFKKPI----SRIISNMCQS 323
            |.|||||.               ||.|||....|.::.|..:|     .|:    ....|....|
  Fly   335 RGHYNPNH---------------SGSSGGYNNNGNNTFGGENN-----HPVHGASESASSGTGPS 379

  Fly   324 RVSQLAVPRTNDNERPRLQLKPRTIAAPINAVAETKQSASIFGNAKPREE 373
            ..:|.||  .:|::||:|.|||||:.||||::|||||:|.|||.||||::
  Fly   380 SSNQFAV--RDDDDRPKLVLKPRTVTAPINSLAETKQAALIFGKAKPRDD 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4H1	NP_001285330.1	RRM	<19..>139	CDD:223796	80/151 (53%)
		RRM_eIF4H	28..106	CDD:240847	60/77 (78%)
eIF4H2	NP_001263122.1	RRM	<58..247	CDD:223796	89/188 (47%)
		RRM_SF	62..140	CDD:302621	60/77 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435321
Domainoid	1	1.000	53	1.000	Domainoid score	I4223
eggNOG	1	0.900	-	-		E33208_3BCZ7
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	67	1.000	Inparanoid score	I2498
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1530583at2759
OrthoFinder	1	1.000	-	-		FOG0006177
OrthoInspector	1	1.000	-	-		otm24970
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23236
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4457
	10	9.900