Protein Alignment eIF4H1 and sce3

DIOPT Version :9

• Sequence 1: NP_001285330.1
• Gene: eIF4H1 / 49809
• FlyBaseID: FBgn0262734
• Length: 388
• Species: Drosophila melanogaster
• Sequence 2: NP_595728.1
• Gene: sce3 / 2540528
• PomBaseID: SPBC18H10.04c
• Length: 388
• Species: Schizosaccharomyces pombe
• Alignment Length: 410
• Identity: 88/410 - (21%)
• Similarity: 117/410 - (28%)
• Gaps: 193/410 - (47%)

  Fly     7 YEHARS----------GFGGDRASKQLPTEPPFIAFVGNLPQGLVQGDVIKIFQDFEVKYVRLVK 61
            :|..||          |.|..|.:..:|:||||.|.||||...|.:.|:...|.: .|..:|||.
pombe    62 FESVRSPPESRREGGMGSGYQRDAIPIPSEPPFTAHVGNLSFDLTENDLGDFFGE-GVTSIRLVI 125

  Fly    62 DRETDQFKGFCYVEFETLDNLERALECDGRIKLDDLSAPLRIDIADRRKNDRPGGGVGGGNGGMT 126
            |..|::.:||.||||||.|.|..||...|.   |.:..|:||.:|:.|::             ..
pombe   126 DPLTERSRGFGYVEFETADTLSAALALSGE---DLMGRPVRITVAEPRRS-------------FA 174

  Fly   127 RGDGGRDGFQKRG--PPRQGGSSQSYSRGGPGTGGGGREGGGGSGNRGDSRGSYIDSYGGHNDRS 189
            |.:.....:.:||  ||.:...|.
pombe   175 REERSTGDWVRRGPLPPAEPAESP----------------------------------------- 198

  Fly   190 RGVGGSGAGSGGGMNRGYNDRPANRGRYGSFNNDDRPFERNQDRDRGQREGSYGNQSRDGDRYNN 254
                             :..|..|.||:           |:..||...|.
pombe   199 -----------------FGKRRTNSGRF-----------RDPARDPSDRV--------------- 220

  Fly   255 FNRHRDRERTHYNPNQQSERPSGGMTGLGGGSGGSGGLGVGGGSSMGAIDNFRHFKKPISRIISN 319
              |...||.....|
pombe   221 --REEPREWVRRGP--------------------------------------------------- 232

  Fly   320 MCQSRVSQLAVPRTNDNERPRLQLKPR------TIAAP-INAVAETKQSASIFGNAKP------- 370
                      :|....:|||||.||||      |.|.| ......:|.....||.|||
pombe   233 ----------LPPRESSERPRLNLKPRSSSNVNTEATPSATTTTSSKPKRDPFGGAKPVDNTSVL 287

  Fly   371 --REEKLKELQQNVNHNGDN 388
              .||||.:..|:.... ||
pombe   288 QRVEEKLAKRTQSFRRE-DN 306

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
eIF4H1	NP_001285330.1	RRM	<19..>139	CDD:223796	39/119 (33%)
		RRM_eIF4H	28..106	CDD:240847	33/77 (43%)
sce3	NP_595728.1	RRM	1..255	CDD:223796	72/356 (20%)
		RRM_SF	95..169	CDD:302621	32/77 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I1677
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006177
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23236
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1292
SonicParanoid	1	1.000	-	-		X4457
TreeFam	1	0.960	-	-
	7	7.050