Protein Alignment Spn42Dd and SERPINB12

DIOPT Version :9

• Sequence 1: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: XP_005266835.2
• Gene: SERPINB12 / 89777
• HGNCID: 14220
• Length: 437
• Species: Homo sapiens
• Alignment Length: 413
• Identity: 120/413 - (29%)
• Similarity: 199/413 - (48%)
• Gaps: 61/413 - (14%)

  Fly    20 EIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGL----PSEDKE-------- 72
            :::|.:.|...::|:..||:|:...|.||.:||...:|.::...|..    .:|.||
Human    26 DLFQEIGKDDRHKNIFFSPLSLSAALGMVRLGARSDSAHQIDEVLHFNEFSQNESKEPDPCLKSN 90

  Fly    73 --------------------------------AVAARYGALLNDLQGQEEGPILKLANRIYVNDQ 105
                                            .|:..:|.||:.|...:....|.:|||:|...:
Human    91 KQKVLADSSLEGQKKTTEPLDQQAGSLNNESGLVSCYFGQLLSKLDRIKTDYTLSIANRLYGEQE 155

  Fly   106 YSLNQNYNLAVREPFKSEAESISLTNGP-VAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLV 169
            :.:.|.|...|.:.:.:..||:.....| .:.:.||.||..|:.||||.:....::.::...:||
Human   156 FPICQEYLDGVIQFYHTTIESVDFQKNPEKSRQEINFWVECQSQGKIKELFSKDAINAETVLVLV 220

  Fly   170 NAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLS 234
            ||:|||.:||:.||...|..:.|.:.||::..|:||.|.|.:|..:..::.||::|:.|....||
Human   221 NAVYFKAKWETYFDHENTVDAPFCLNANENKSVKMMTQKGLYRIGFIEEVKAQILEMRYTKGKLS 285

  Fly   235 MTIFLPR----EVEGLSALEEKIV-------GFARPLVAKEVYLKLPKFKIEFRDELKETLEKLG 288
            |.:.||.    .::||..||.||.       ..:..:..:.|.|..|:|.:|...:|...|:.:|
Human   286 MFVLLPSHSKDNLKGLEELERKITYEKMVAWSSSENMSEESVVLSFPRFTLEDSYDLNSILQDMG 350

  Fly   289 IRELFTD-KSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSVAVTNRAGFS-TFLMADH 351
            |.::|.: ::||:|: :......:|::.||.|:||:|.|.:||.||...|:.|:..| ....|:|
Human   351 ITDIFDETRADLTGI-SPSPNLYLSKIIHKTFVEVDENGTQAAAATGAVVSERSLRSWVEFNANH 414

  Fly   352 PFAFVIR--DANTIYFQGRVVSP 372
            ||.|.||  ...||.|.|||.||
Human   415 PFLFFIRHNKTQTILFYGRVCSP 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	116/408 (28%)
SERPINB12	XP_005266835.2	ovalbumin_like	16..437	CDD:239014	118/411 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	1	0.900	-	-		E33208_3BBFJ
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	1	1.000	-	-		FOG0000050
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.880