Protein Alignment Spn42Dd and SERPINB7

DIOPT Version :9

• Sequence 1: NP_001163067.1
• Gene: Spn42Dd / 49808
• FlyBaseID: FBgn0028988
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_001035237.1
• Gene: SERPINB7 / 8710
• HGNCID: 13902
• Length: 380
• Species: Homo sapiens
• Alignment Length: 387
• Identity: 119/387 - (30%)
• Similarity: 199/387 - (51%)
• Gaps: 31/387 - (8%)

  Fly    10 VTSVACQTSKEIYQLLSKSHTNQ---NLVVSPVSIETILSMVFMGAEGSTAKELQ--------SA 63
            :.|:|...::..:.|..:...||   |:..|.:|:...|::|.:||:..:..::.        |.
Human     1 MASLAAANAEFCFNLFREMDDNQGNGNVFFSSLSLFAALALVRLGAQDDSLSQIDKLLHVNTASG 65

  Fly    64 LGLPSEDKEAVAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESIS 128
            .|..|..:..:.::...:.:|:....:...|.:.|.::....|..:::|.....:.:.::.|.:.
Human    66 YGNSSNSQSGLQSQLKRVFSDINASHKDYDLSIVNGLFAEKVYGFHKDYIECAEKLYDAKVERVD 130

  Fly   129 LTNGPVAAER-INQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTF 192
            .||......| ||:||.::|.||||.:|..|.::|....:||||:||||:|:|.|..::|....|
Human   131 FTNHLEDTRRNINKWVENETHGKIKNVIGEGGISSSAVMVLVNAVYFKGKWQSAFTKSETINCHF 195

  Fly   193 QVTANKSVPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSMTIFLPREVEGLSALEEKIVGF- 256
            :........|.||.|...|..:...|...:::||.| |..::|.:.||.  ..||.:|.|:. |
Human   196 KSPKCSGKAVAMMHQERKFNLSVIEDPSMKILELRY-NGGINMYVLLPE--NDLSEIENKLT-FQ 256

  Fly   257 -------ARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTD-KSDLSGLFADKSGGK--V 311
                   .|.:.:|.|.:..|:||||...|:|:.|..||::::|.: |:||||:   .|||:  :
Human   257 NLMEWTNPRRMTSKYVEVFFPQFKIEKNYEMKQYLRALGLKDIFDESKADLSGI---ASGGRLYI 318

  Fly   312 SQVSHKAFLEVNEEGAEAAGAT-SVAVTNRAGFSTFLMADHPFAFVIRDANTIYFQGRVVSP 372
            |::.||:::||.|||.||..|| |..|..:...||...|||||.||||..:.|.|.|:|..|
Human   319 SRMMHKSYIEVTEEGTEATAATGSNIVEKQLPQSTLFRADHPFLFVIRKDDIILFSGKVSCP 380

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	115/376 (31%)
SERPINB7	NP_001035237.1	serpinB7_megsin	1..380	CDD:381032	118/385 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	221	1.000	Domainoid score	I2614
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	222	1.000	Inparanoid score	I3541
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57242
OrthoDB	1	1.010	-	-		D556621at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8652
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	6.980