DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Spn42Dd and zgc:174259

DIOPT Version :9

Sequence 1:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster
Sequence 2:	XP_021331992.1	Gene:	zgc:174259 / 791587	ZFINID:	ZDB-GENE-080213-10	Length:	410	Species:	Danio rerio

Alignment Length:	413	Identity:	110/413 - (26%)
Similarity:	205/413 - (49%)	Gaps:	58/413 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 IFLWVTS---VACQTSKEIYQ-------------------------LLSKSHTNQNLVVSPVSIE 42
            :|||:..   |.|...:.:.|                         :.|..:.::|:..||.|:.
Zfish     6 VFLWICGFAIVVCGNQETLQQPPISAKLPSLINMNNDFAFHLYKRLIESPDYQSKNIFFSPFSVS 70

  Fly    43 TILSMVFMGAEGSTAKELQSALGLPSE--DKEAVAARYGALLNDLQGQEEGPILKLANRIYVNDQ 105
            ..||.:.:||.|.|.::|.|.:|..|.  ..|.:...:.:||.|: |...|..:.:...:|.:|:
Zfish    71 MALSELSLGAGGDTKQQLLSGIGYSSAIFSTEEMHQLFHSLLEDI-GNRTGVDIDVGTALYASDR 134

  Fly   106 YSLNQNYNLAVREPFKSEAESISLTNGPVAAERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVN 170
            :..:..:...::|.:.|:..::.. :.....::||::|.::|.|||...:|  .:.:|...:|:.
Zfish   135 FKPHSKFLEDMKEFYHSDGFTVDF-SVKETVDQINKYVEEKTHGKINQAVD--DLDADTFMVLLT 196

  Fly   171 AIYFKGQWESKFDPAKTRASTFQVTANKSVPVQMMAQMGTFRANYFRDLDAQVIELPYLNSNLSM 235
            .|||||:|:..|:|..|..|||.:....:||||||.|....:..|..:|..:|:.|.| |.:.||
Zfish   197 YIYFKGKWDKPFNPKTTSESTFHIDDKTTVPVQMMHQYERLKVYYDAELSTKVLCLDY-NDSFSM 260

  Fly   236 TIFLP---------REVEGLSALEEKIVGFARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRE 291
            .:.:|         :::| ::...:.:..:.|.:..::|.:.:||..::....||:.|:.:|:.:
Zfish   261 FLAVPDVHMGRKTIKDLE-MTVSRQHVEKWRRSVSERKVDIYVPKLSLKTSYSLKDILKGMGMAD 324

  Fly   292 LFTDKSDLSGLFADKSGGKVSQVSHKAFLEVNEEGAEAAGATSVAVTNRAGFSTF-----LMADH 351
            :|:||:|.:|:..:|.  .||:|.|||.|:::|:|..||..|:|.:.    |.::     |..|.
Zfish   325 MFSDKADFTGVSEEKI--YVSKVLHKATLDIDEKGTTAAAVTTVHLR----FMSYSPMSDLSFDR 383

  Fly   352 PFAFVIRDA--NTIYFQGRVVSP 372
            ||...|.|.  :.|.|.|:||:|
Zfish   384 PFMIFITDQTNDNILFVGKVVNP 406

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	102/395 (26%)
zgc:174259	XP_021331992.1	alpha-1-antitrypsin_like	39..403	CDD:239011	101/375 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.010