DRSC/TRiP Functional Genomics Resources

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Protein Alignment Spn42Dd and SERPING1

DIOPT Version :9

Sequence 1:NP_001163067.1 Gene:Spn42Dd / 49808 FlyBaseID:FBgn0028988 Length:372 Species:Drosophila melanogaster
Sequence 2:NP_000053.2 Gene:SERPING1 / 710 HGNCID:1228 Length:500 Species:Homo sapiens


Alignment Length:384 Identity:110/384 - (28%)
Similarity:173/384 - (45%) Gaps:64/384 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 SKEIYQLLS-KSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLPSEDKEAVAARYGAL 81
            |.::|...| ......|:..||.||.::|:.|.:||..:|...|:|.|..|.:        :..:
Human   150 SLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKD--------FTCV 206

  Fly    82 LNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPF-------KSEAESISLTNGPVAAERI 139
            ...|:|.....:..::...:..|         ||:|:.|       .|.:..:...|.....|.|
Human   207 HQALKGFTTKGVTSVSQIFHSPD---------LAIRDTFVNASRTLYSSSPRVLSNNSDANLELI 262

  Fly   140 NQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSVPVQM 204
            |.||...|:.||..::|  |:.||.:.:|:||||...:|::.|||.|||...|.. .|..:.|.|
Human   263 NTWVAKNTNNKISRLLD--SLPSDTRLVLLNAIYLSAKWKTTFDPKKTRMEPFHF-KNSVIKVPM 324

  Fly   205 MAQMGTFRANYFRD--LDAQVIELPYLNSNLSMTIFLPREVE-GLSALEEKIVGFARPLVAKEV- 265
            | ....:...:|.|  |.|:|.:| .|:.|||:.|.:|:.:: .|..:|:.:    .|.|.|.: 
Human   325 M-NSKKYPVAHFIDQTLKAKVGQL-QLSHNLSLVILVPQNLKHRLEDMEQAL----SPSVFKAIM 383

  Fly   266 -----------YLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLS--GLFADKSGGKVSQVSHK 317
                       .|.||:.|:....::...:|||   |.|....||:  ||..|.. .:||.:.|:
Human   384 EKLEMSKFQPTLLTLPRIKVTTSQDMLSIMEKL---EFFDFSYDLNLCGLTEDPD-LQVSAMQHQ 444

  Fly   318 AFLEVNEEGAEAAGATSVAVTNRAGFSTFLM--ADHPFAFVIRDANTIY--FQGRVVSP 372
            ..||:.|.|.|||.|::::|..     |.|:  ...||.||:.|....:  |.|||..|
Human   445 TVLELTETGVEAAAASAISVAR-----TLLVFEVQQPFLFVLWDQQHKFPVFMGRVYDP 498

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Spn42DdNP_001163067.1 SERPIN 16..369 CDD:238101 107/379 (28%)
SERPING1NP_000053.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 20..43
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 65..118
7 X 4 AA tandem repeats of [QE]-P-T-[TQ] 85..119
C1_inh 145..495 CDD:239005 107/379 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11461
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
22.010

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